6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

Product Name: 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
CAS No.: 356560-80-0
Chemical Name: 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
Synonyms: 6-BroMo[1,2,4]triazolo[1,...;6-Bromo[1,2,4]triazolo[1,5-α]pyridine;6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE;[1,2,4]Triazolo[1,5-a]pyridine,6-broMo-;356560-80-0;6-Bromo[1,2,4]triazolo[1,5-a]pyridine 96%;6-Bromo-[1,2,4]triazolo[1,5-a]pyridine;6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE ISO 9001：2015 REACH
CBNumber: CB3837728
Molecular Formula: C6H4BrN3
Formula Weight: 198.02
MOL File: 356560-80-0.mol

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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Property

Melting point:: 100-102
Density: 1.89±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
pka: 1.46±0.30(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C6H4BrN3/c7-5-1-2-6-8-4-9-10(6)3-5/h1-4H
InChIKey: CXRXKDSDRWLKTK-UHFFFAOYSA-N
SMILES: C12=NC=NN1C=C(Br)C=C2

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-24/25
WGK Germany: 3
Hazard Note: Harmful/Irritant/Keep Cold
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00141
Product name: 6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Purity: Aldrich
Packaging: 1g
Price: $259
Updated: 2025/07/31

Sigma-Aldrich

Product number: 751006
Product name: 6-Bromo-[1,2,4]triazolo[1,5-a]pyridine
Purity: 97%
Packaging: 500mg
Price: $89.7
Updated: 2023/06/20

Usbiological

Product number: 005026
Product name: 6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Packaging: 1g
Price: $425
Updated: 2021/12/16

TRC

Product number: B688349
Product name: 6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Packaging: 1g
Price: $140
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19035
Product name: 6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Packaging: 2g
Price: $150
Updated: 2021/12/16

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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

A selective inhibitor of ALK5 kinase

Synthesis

138888-98-9

356560-80-0

General procedure: N'-(5-bromo-2-pyridinyl)-N,N-dimethylformamidine (4 g, 17.54 mmol, 1.00 eq.) was dissolved in methanol (40 mL) under nitrogen protection and cooled to 0 °C. Subsequently, pyridine (4 mL, 2.00 eq.) and aminoxysulfonic acid (3.6 g, 31.83 mmol, 1.30 eq.) were added sequentially. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was diluted with ethyl acetate (150 mL) and washed sequentially with saturated aqueous sodium carbonate solution (50 mL x 1) and water (50 mL x 2). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of ethyl acetate/hexane (1:1) to afford 6-bromo-[1,2,4]triazolo[1,5-A]pyridine 2.5 g (72% yield) as a solid. LC/MS (Method D, ESI): retention time = 1.1 min, m/z = 198.0 [M+H]+.

References

[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 141
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 92
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 67
[4] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0206
[5] Patent: WO2013/130943, 2013, A1. Location in patent: Paragraph 0214

6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Suppliers

Canada 1 China 175 Germany 1 India 3 United Kingdom 2 United States 18 Global 200

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 690
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shanghai Kahn Pharmaceutical Co., Ltd.

Tel: 021-34979681; 17701870669
Fax: 021-34979681
Email: 41513101@qq.com
Country: China
ProdList: 1785
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
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Shangchem Co., Ltd.

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Fax: +86-21-68182121
Country: China
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ChengDu TongChuangYuan Pharmaceutical Co.Ltd

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Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 510
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
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View Lastest Price from 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE manufacturers

Dideu Industries Group Limited

Product: 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

Career Henan Chemical Co

Product: 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 200KG
Release date: 2018-08-19

Career Henan Chemical Co

Product: 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500KG
Release date: 2018-08-19

356560-80-0, 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINERelated Search:

6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%,6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE,6-BROMO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 5-(1H-Imidazol-1-yl)-2-pyridinamine 1-Methyl-1H-pyrazol-4-aMine dihydrochloride 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (R)-1-(4-FLUOROPHENYL)ETHANOL 4-bromo-1-methylpyrazole-3-carboxy acid 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 2,5-DIBROMO-3-AMINOPYRIDINE 4,5-Dihydrooxazole, 2-vinyl- 1-methyl-1H-pyrazol-4-amine 1H-Pyrazolo[3,4-b]pyridine, 6-broMo- 1H-Pyrazolo[4,3-c]pyridine, 6-broMo- 8-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 8-bromo-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-2-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

6-Bromo[1,2,4]triazolo[1,5-a]pyridine 96%

6-Bromo[1,2,4]triazolo[1,5-α]pyridine

6-BroMo[1,2,4]triazolo[1,...

[1,2,4]Triazolo[1,5-a]pyridine,6-broMo-

6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE ISO 9001：2015 REACH

6-Bromo-[1,2,4]triazolo[1,5-<i>a</i>]pyridine

356560-80-0

Heterocycle-Pyridine series

Heterocyclic Compounds

Bases & Related Reagents

Heterocycles

Nucleotides

blocks

Bromides

Pyridines