ChemicalBook > CAS DataBase List > 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

Product Name
6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
CAS No.
356560-80-0
Chemical Name
6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
Synonyms
6-BroMo[1,2,4]triazolo[1,...;6-Bromo[1,2,4]triazolo[1,5-α]pyridine;6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE;[1,2,4]Triazolo[1,5-a]pyridine,6-broMo-;356560-80-0;6-Bromo[1,2,4]triazolo[1,5-a]pyridine 96%;6-Bromo-[1,2,4]triazolo[1,5-a]pyridine;6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE ISO 9001：2015 REACH
CBNumber
CB3837728
Molecular Formula
C6H4BrN3
Formula Weight
198.02
MOL File
356560-80-0.mol
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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Property

Melting point:
100-102
Density 
1.89±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Solid
pka
1.46±0.30(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C6H4BrN3/c7-5-1-2-6-8-4-9-10(6)3-5/h1-4H
InChIKey
CXRXKDSDRWLKTK-UHFFFAOYSA-N
SMILES
C12=NC=NN1C=C(Br)C=C2
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-24/25
WGK Germany 
3
Hazard Note 
Harmful/Irritant/Keep Cold
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00141
Product name
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Purity
Aldrich
Packaging
1g
Price
$259
Updated
2025/07/31
Sigma-Aldrich
Product number
751006
Product name
6-Bromo-[1,2,4]triazolo[1,5-a]pyridine
Purity
97%
Packaging
500mg
Price
$89.7
Updated
2023/06/20
TRC
Product number
B688349
Product name
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Packaging
1g
Price
$140
Updated
2021/12/16
Usbiological
Product number
005026
Product name
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Packaging
1g
Price
$425
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK790691
Product name
6-Bromo[1,2,4]triazolo[1,5-a]pyridine
Purity
95%
Packaging
250mg
Price
$33
Updated
2021/12/16
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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

A selective inhibitor of ALK5 kinase

Synthesis

138888-98-9

356560-80-0

General procedure: N'-(5-bromo-2-pyridinyl)-N,N-dimethylformamidine (4 g, 17.54 mmol, 1.00 eq.) was dissolved in methanol (40 mL) under nitrogen protection and cooled to 0 °C. Subsequently, pyridine (4 mL, 2.00 eq.) and aminoxysulfonic acid (3.6 g, 31.83 mmol, 1.30 eq.) were added sequentially. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was diluted with ethyl acetate (150 mL) and washed sequentially with saturated aqueous sodium carbonate solution (50 mL x 1) and water (50 mL x 2). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent of ethyl acetate/hexane (1:1) to afford 6-bromo-[1,2,4]triazolo[1,5-A]pyridine 2.5 g (72% yield) as a solid. LC/MS (Method D, ESI): retention time = 1.1 min, m/z = 198.0 [M+H]+.

References

[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 141
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 92
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 67
[4] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0206
[5] Patent: WO2013/130943, 2013, A1. Location in patent: Paragraph 0214

6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE Suppliers

Canada 1 China 175 Germany 1 India 3 United Kingdom 2 United States 18 Global 200
ACTIVATE SCIENTIFIC GmbH
Tel
--
Fax
--
Email
info@activate-scientific.com
Country
Germany
ProdList
2856
Advantage
61
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View Lastest Price from 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE manufacturers

Dideu Industries Group Limited
Product
6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Career Henan Chemical Co
Product
6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
200KG
Release date
2018-08-19
Career Henan Chemical Co
Product
6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 356560-80-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

356560-80-0, 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINERelated Search:

6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%,6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE,6-BROMO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 5-(1H-Imidazol-1-yl)-2-pyridinamine 1-Methyl-1H-pyrazol-4-aMine dihydrochloride 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (R)-1-(4-FLUOROPHENYL)ETHANOL 4-bromo-1-methylpyrazole-3-carboxy acid 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 2,5-DIBROMO-3-AMINOPYRIDINE 4,5-Dihydrooxazole, 2-vinyl- 1-methyl-1H-pyrazol-4-amine 1H-Pyrazolo[3,4-b]pyridine, 6-broMo- 1H-Pyrazolo[4,3-c]pyridine, 6-broMo- 8-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 8-bromo-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid 5-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 6-BROMO-2-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

  • 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
  • 6-Bromo[1,2,4]triazolo[1,5-a]pyridine 96%
  • 6-Bromo[1,2,4]triazolo[1,5-α]pyridine
  • 6-BroMo[1,2,4]triazolo[1,...
  • [1,2,4]Triazolo[1,5-a]pyridine,6-broMo-
  • 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE ISO 9001：2015 REACH
  • <font color="#ff0000">356560-80-0</font>
  • 6-Bromo-[1,2,4]triazolo[1,5-<i>a</i>]pyridine
  • 356560-80-0
  • Heterocycle-Pyridine series
  • Heterocyclic Compounds
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • blocks
  • Bromides
  • Pyridines