5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

Product Name: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
CAS No.: 51985-95-6
Chemical Name: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms: Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate;NSC 338308;Methyl 5-hydroxy-1-methyl-3-pyrazolecarboxylate;methyl 2-methyl-3-oxo-1H-pyrazole-5-carboxylate;methyl 5-hydroxy-1-methyl-pyrazole-3-carboxylate;1H-Pyrazole-3-carboxylic acid, 1-methyl-, methyl ester;Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 97%;Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate;Methyl 1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate;5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
CBNumber: CB21119246
Molecular Formula: C6H8N2O3
Formula Weight: 156.14
MOL File: 51985-95-6.mol

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5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Property

Melting point:: 195-200°C
Boiling point:: 330.7±22.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 8.26±0.28(Predicted)
color: Pale brown
InChI: InChI=1S/C6H8N2O3/c1-8-5(9)3-4(7-8)6(10)11-2/h3,9H,1-2H3
InChIKey: IWOKRTHKTAEDLP-UHFFFAOYSA-N
SMILES: N1(C)C(O)=CC(C(OC)=O)=N1

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Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 754609
Product name: Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate
Purity: 97%
Packaging: 1g
Price: $135
Updated: 2023/06/20

TRC

Product number: H999853
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicAcidMethylEster
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR346186
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicacidmethylester
Packaging: 1g
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-ZK
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester
Packaging: 1g
Price: $88
Updated: 2021/12/16

Matrix Scientific

Product number: 059093
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acidmethyl ester
Purity: 95%+
Packaging: 1g
Price: $110
Updated: 2021/12/16

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5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

58364-79-7

51985-95-6

b) Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate (12.2 g, 65 mmol) was dissolved in xylene (65 mL) and p-toluenesulfonic acid (0.9 g, 4.7 mmol) was added. The reaction mixture was heated to reflux for 6 hours. Upon completion of the reaction, it was cooled to room temperature and stirred overnight. The precipitated solid was collected by filtration and dissolved in ethyl acetate. The organic phase was washed sequentially with sodium bicarbonate solution and saturated brine and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to give methyl 1-methyl-5-hydroxypyrazole-3-carboxylate (7.49 g, 74% yield) as a light brown solid. The purity of the product was improved by diisopropyl ether milling. Mass spectrometry analysis showed: m/e = 157.2 [M + H]+.

References

[1] Patent: WO2010/127975, 2010, A1. Location in patent: Page/Page column 131

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Suppliers

China 94 India 1 Switzerland 2 United Kingdom 1 United States 12 Global 110

Nanjing Chemcn Pharmaceutical Co., Ltd.

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View Lastest Price from 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER manufacturers

Shanghai Rlavie Technology Co ltd

Product: methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 51985-95-6
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

Career Henan Chemical Co

Product: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 51985-95-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-11

51985-95-6, 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Related Search:

Ethyl 5-Oxo-4,5-dihydro-1H-pyrazole-3-carboxylate PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID (S)-1-(4-FLUOROPHENYL)ETHANOL 1-Methyl-1H-pyrazol-4-aMine dihydrochloride 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (R)-1-(4-FLUOROPHENYL)ETHANOL 4-bromo-1-methylpyrazole-3-carboxy acid 2,5-DIBROMO-3-AMINOPYRIDINE 4,5-Dihydrooxazole, 2-vinyl- 1-methyl-1H-pyrazol-4-amine Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 3-Ethoxycarbonyl-5-hydroxy-1-sulfolanylpyrazole ETHYL 6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXYLATE 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER ETHYL 2-[5-HYDROXY-3-(METHOXYCARBONYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE-4-CARBOXYLATE 1-(4-CARBOXY-PHENYL)-5-HYDROXY-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER ethyl 5-hydroxy-1-[(methylamino)carbonyl]-1H-pyrazole-3-carboxylate

1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester

Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 97%

Methyl 5-hydroxy-1-methyl-3-pyrazolecarboxylate

NSC 338308

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

1H-Pyrazole-3-carboxylic acid, 1-methyl-, methyl ester

Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate

Methyl 1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-methyl-, methyl ester

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER ISO 9001：2015 REACH

methyl 5-hydroxy-1-methyl-pyrazole-3-carboxylate

methyl 2-methyl-3-oxo-1H-pyrazole-5-carboxylate

Methyl 5-hydroxy-1-methyl-1<i>H</i>-pyrazole-3-carboxylate

51985-95-6