ChemicalBook > CAS DataBase List > 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

Product Name: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
CAS No.: 51985-95-6
Chemical Name: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms: Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate;NSC 338308;Methyl 5-hydroxy-1-methyl-3-pyrazolecarboxylate;methyl 2-methyl-3-oxo-1H-pyrazole-5-carboxylate;methyl 5-hydroxy-1-methyl-pyrazole-3-carboxylate;1H-Pyrazole-3-carboxylic acid, 1-methyl-, methyl ester;Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 97%;Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate;Methyl 1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate;5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER
CBNumber: CB21119246
Molecular Formula: C6H8N2O3
Formula Weight: 156.14
MOL File: 51985-95-6.mol

Less

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Property

Melting point:: 195-200°C
Boiling point:: 330.7±22.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 8.26±0.28(Predicted)
color: Pale brown
InChI: InChI=1S/C6H8N2O3/c1-8-5(9)3-4(7-8)6(10)11-2/h3,9H,1-2H3
InChIKey: IWOKRTHKTAEDLP-UHFFFAOYSA-N
SMILES: N1(C)C(O)=CC(C(OC)=O)=N1

Less

Safety

WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933199090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 754609
Product name: Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate
Purity: 97%
Packaging: 1g
Price: $135
Updated: 2023/06/20

TRC

Product number: H999853
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicAcidMethylEster
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR346186
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicacidmethylester
Packaging: 1g
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-ZK
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester
Packaging: 1g
Price: $88
Updated: 2021/12/16

Matrix Scientific

Product number: 059093
Product name: 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acidmethyl ester
Purity: 95%+
Packaging: 1g
Price: $110
Updated: 2021/12/16

Less

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

58364-79-7

51985-95-6

b) Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate (12.2 g, 65 mmol) was dissolved in xylene (65 mL) and p-toluenesulfonic acid (0.9 g, 4.7 mmol) was added. The reaction mixture was heated to reflux for 6 hours. Upon completion of the reaction, it was cooled to room temperature and stirred overnight. The precipitated solid was collected by filtration and dissolved in ethyl acetate. The organic phase was washed sequentially with sodium bicarbonate solution and saturated brine and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to give methyl 1-methyl-5-hydroxypyrazole-3-carboxylate (7.49 g, 74% yield) as a light brown solid. The purity of the product was improved by diisopropyl ether milling. Mass spectrometry analysis showed: m/e = 157.2 [M + H]+.

References

[1] Patent: WO2010/127975, 2010, A1. Location in patent: Page/Page column 131

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Suppliers

China 94 India 1 Switzerland 2 United Kingdom 1 United States 12 Global 110

Nanjing Chemcn Pharmaceutical Co., Ltd.

Tel: 18114022054; 18114022054
Fax: +86-25-58857385
Email: 3317707757@qq.com
Country: China
ProdList: 301
Advantage: 55

Ningbo Zeyu Chemical Technology Co., Ltd

Tel: 15066123231
Email: 2278736577@qq.com
Country: China
ProdList: 492
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Wuhan Luohua Medical Technology Co.,Ltd.

Tel: 13477084141; 13477084141
Fax: +86(27)65566697
Email: sales@luohuapharm.com
Country: China
ProdList: 468
Advantage: 60

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Acorn PharmaTech Co., Ltd.

Tel: 025-58395930
Fax: 025-5861-9182
Email: sales@acornpharma.com
Country: China
ProdList: 982
Advantage: 60

Chengdu HappySyn Pharmaceutical Technology Co., Ltd.

Tel: 028-85114309 18982182443
Email: yangli@happysyn.com
Country: China
ProdList: 2151
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
Fax: 021-50315529
Email: mychess007@163.com
Country: China
ProdList: 1994
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD

Tel: 0571-87322520 18957127338
Fax: QQ:3007632051
Email: sales@zetchem.com
Country: China
ProdList: 467
Advantage: 55

Shanghai Boyners Pharm-Tech Co., Ltd.

Tel: 13817873692
Fax: 021-31329586
Email: mkt@boynerspharm.com
Country: China
ProdList: 1707
Advantage: 55

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Jiaxing Rich Biological Technology Co., Ltd.

Tel: 0573-11111111-1111 18969316891
Fax: -
Email: richmol@163.com
Country: China
ProdList: 449
Advantage: 50

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Nanjing YaoCheng Pharmaceutical Co., Ltd.

Tel: 025-57043319 15261831516
Fax: 025-57043319
Email: 307514552@qq.com
Country: China
ProdList: 251
Advantage: 50

Jinan SanZhi Pharmaceutical Technology Co., Ltd.

Tel: 15053191807
Fax: -
Email: sales_sanzhi@163.com
Country: China
ProdList: 286
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Cochemical Ltd.

Tel: 029-86115547 17791676824
Fax: 021-51602123
Email: sales@cochemical.com
Country: China
ProdList: 4006
Advantage: 58

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22345
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai ZiHao Pharmaceutical Co., Ltd.

Tel: 021-13482410-12 13482410112
Fax: -
Email: 362383684@qq.com
Country: China
ProdList: 737
Advantage: 58

Yujinpharma(Tianjin) Technology Co.,Ltd.

Tel: 13370351217 kungfu1217@1
Fax: QQ1400885609
Email: kungfu1217@163.com
Country: China
ProdList: 2720
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Shanghai Rlavie Technology Co ltd

Tel: +86-021-67759270 +8617717059219
Fax: 021-67759270
Email: sales@rlavie.com
Country: China
ProdList: 1030
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 8025
Advantage: 58

Shanxi Xuanran Import and Export Trade Co., Ltd.

Tel: +8617735180244
Email: mike_yan@xuanranglobal.com
Country: CHINA
ProdList: 4017
Advantage: 58

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Zhende Chemical Technology (Shanghai) Co., Ltd.

Tel: 15601952568
Fax: 3004479441
Email: sales4@myuchem.com
Country: China
ProdList: 2988
Advantage: 58

Shanghai Sunmonth Technology Co., LTD

Tel: 15216675652
Email: xuanyuelj@163.com
Country: China
ProdList: 2864
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Chengdu ruihede Medical Technology Co., Ltd

Tel: 17381862311; 17381862311
Email: sales2@ruihede.cn
Country: China
ProdList: 281
Advantage: 58

Less

View Lastest Price from 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER manufacturers

Shanghai Rlavie Technology Co ltd

Product: methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 51985-95-6
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

Career Henan Chemical Co

Product: 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 51985-95-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-11

51985-95-6, 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER Related Search:

Ethyl 5-Oxo-4,5-dihydro-1H-pyrazole-3-carboxylate PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID (S)-1-(4-FLUOROPHENYL)ETHANOL 1-Methyl-1H-pyrazol-4-aMine dihydrochloride 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (R)-1-(4-FLUOROPHENYL)ETHANOL 4-bromo-1-methylpyrazole-3-carboxy acid 2,5-DIBROMO-3-AMINOPYRIDINE 4,5-Dihydrooxazole, 2-vinyl- 1-methyl-1H-pyrazol-4-amine Ethyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 3-Ethoxycarbonyl-5-hydroxy-1-sulfolanylpyrazole ETHYL 6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXYLATE 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER ETHYL 2-[5-HYDROXY-3-(METHOXYCARBONYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE-4-CARBOXYLATE 1-(4-CARBOXY-PHENYL)-5-HYDROXY-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER ethyl 5-hydroxy-1-[(methylamino)carbonyl]-1H-pyrazole-3-carboxylate

1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester

Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate 97%

Methyl 5-hydroxy-1-methyl-3-pyrazolecarboxylate

NSC 338308

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER

1H-Pyrazole-3-carboxylic acid, 1-methyl-, methyl ester

Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate

Methyl 1-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate

1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-methyl-, methyl ester

5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER ISO 9001：2015 REACH

methyl 5-hydroxy-1-methyl-pyrazole-3-carboxylate

methyl 2-methyl-3-oxo-1H-pyrazole-5-carboxylate

Methyl 5-hydroxy-1-methyl-1<i>H</i>-pyrazole-3-carboxylate

51985-95-6