(4R)-4-Methyl-2-oxazolidinone

Product Name: (4R)-4-Methyl-2-oxazolidinone
CAS No.: 4042-43-7
Chemical Name: (4R)-4-Methyl-2-oxazolidinone
Synonyms: (4R)-4-Methyl-2-oxazolidinone;(R)-4-methyl-2-azolealkaneone;2-Oxazolidinone,4-methyl-,(4S)-;2-Oxazolidinone, 4-methyl-, (4R)-;(4R)-4-Methyl-2-oxazolidinone4042-43-7;Benzenepropanoicacid,6-chloro-β-oxo-,methylester
CBNumber: CB4853602
Molecular Formula: C4H7NO2
Formula Weight: 101.1
MOL File: 4042-43-7.mol

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(4R)-4-Methyl-2-oxazolidinone Property

Melting point:: 45.9 °C
Boiling point:: 302.6±9.0 °C(Predicted)
Density: 1.095±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 12.84±0.40(Predicted)
Appearance: White to light yellow Solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

aablocks

Product number: AA0072UK
Product name: (R)-4-Methyloxazolidin-2-one
Purity: 97%
Packaging: 250mg
Price: $19
Updated: 2026/05/28

aablocks

Product number: AA0072UK
Product name: (R)-4-Methyloxazolidin-2-one
Purity: 98%
Packaging: 1g
Price: $24
Updated: 2026/05/28

aablocks

Product number: AA0072UK
Product name: (R)-4-Methyloxazolidin-2-one
Purity: 98%
Packaging: 5g
Price: $78
Updated: 2026/05/28

aablocks

Product number: AA0072UK
Product name: (R)-4-Methyloxazolidin-2-one
Purity: 95%
Packaging: 25g
Price: $363
Updated: 2026/05/28

ACHEMBLOCK

Product number: U136951
Product name: (R)-4-Methyloxazolidin-2-one
Purity: 95%
Packaging: 25G
Price: $365
Updated: 2026/05/27

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(4R)-4-Methyl-2-oxazolidinone Chemical Properties,Usage,Production

Synthesis

75-44-5

35320-23-1

4042-43-7

D-alaninol (8.65 g, 0.12 mmol) was dissolved in a mixed solvent of toluene and KOH aqueous solution (124 mL, 12.5% aqueous solution, 0.28 mmol) at 0 °C. Phosgene (72.7 mL, 20% toluene solution, 0.14 mmol) was added slowly dropwise, and the dropwise acceleration was controlled to maintain the internal temperature of the reaction system below 5 °C. After the dropwise addition, the reaction was continued to be stirred at 0 °C for 40 min. After completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure. The crude product was dissolved with industrial methanol, filtered to remove insoluble matter, and the filtrate was concentrated under reduced pressure to obtain the crude product. The crude product was purified by silica gel fast column chromatography (eluent gradient: 40-100% cyclohexane solution of ethyl acetate), and 10.4 g (90% yield) of (R)-4-methyl-2-oxazolidinone was finally obtained as a white solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 6.00 (broad single peak, 1H), 4.50 (triple peak, J=6.5 Hz, 1H), 4.07-3.97 (multiple peaks, 1H), 3.95 (double dichotomous peaks, J=7.8,6.2 Hz, 1H), and 1.30 (dichotomous peak, J=6.1 Hz, 3H).

References

[1] Patent: WO2017/1645, 2017, A1. Location in patent: Page/Page column 78; 79
[2] Patent: US2017/2022, 2017, A1. Location in patent: Paragraph 0185-0186

(4R)-4-Methyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R)-4-Methyl-2-oxazolidinone Suppliers

China 48 India 2 United States 5 Global 55

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View Lastest Price from (4R)-4-Methyl-2-oxazolidinone manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: (4R)-4-Methyl-2-oxazolidinone 4042-43-7
Price: US $3.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-07-29

4042-43-7, (4R)-4-Methyl-2-oxazolidinoneRelated Search:

(R)-(-)-3-PROPIONYL-4-ISOPROPYL-2-OXAZOLIDINONE (-)-CHIRACAMPHOX (N-CHLOROACETYL)-(4S)-BENZYL-2-OXAZOLIDINONE (R)-(-)-4-Phenyl-2-oxazolidinone (R)-(+)-4-Isopropyl-2-oxazolidinone (4R,5S)-(+)-4-METHYL-5-PHENYL-2-OXAZOLIDINONE (R)-4-Benzyl-2-oxazolidinone (R)-(-)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE N-PROPIONYL-(4S,5R)-4-METHYL- 5-PHENYL-2-OXAZOLIDINONE N-ACETYL-(4R)-ISOPROPYL 2-OXAZOLIDINONE (R)-(-)-5,5-DIMETHYL-4-PHENYL-2-OXAZOLIDINONE N-ACETYL-(4S,5R)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE (N-ACETYL)-(4R)-BENZYL-2-OXAZOLIDINONE Z-D-Phenylalanine N-carboxyanhydride (R)-(+)-4-BENZYL-5,5-DIMETHYL-2-OXAZOLIDINONE 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE N-(DIETHYLPHOSPHONOACETYL) (4R)-BENZYL-2-OXAZOLIDINONE

(4R)-4-Methyl-2-oxazolidinone

(4R)-4-Methyl-2-oxazolidinone4042-43-7

2-Oxazolidinone, 4-methyl-, (4R)-

2-Oxazolidinone,4-methyl-,(4S)-

Benzenepropanoicacid,6-chloro-β-oxo-,methylester

(R)-4-methyl-2-azolealkaneone

4042-43-7