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simfibrate

Product Name
simfibrate
CAS No.
14929-11-4
Chemical Name
simfibrate
Synonyms
CLY-503;Sinfibrate;simfibrate;Cholesolvin;simfibrate USP/EP/BP;1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate];Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate);Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl;Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester;3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
CBNumber
CB4875031
Molecular Formula
C23H26Cl2O6
Formula Weight
469.35
MOL File
14929-11-4.mol
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simfibrate Property

Melting point:
51-53°
Boiling point:
bp0.03 197-200°; bp0.15 220-230°
Density 
1.2623 (estimate)
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Safety

Toxicity
LD50 in mice, rats (g/kg): 3.3-3.5; 7.3-8.0 orally (Nakanishi, J. Pharm. Soc. Japan)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0004178
Product name
SIMFIBRATE
Purity
95.00%
Packaging
1G
Price
$1750
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004178
Product name
SIMFIBRATE
Purity
95.00%
Packaging
5G
Price
$7150
Updated
2021/12/16
Alichem
Product number
14929114
Product name
Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate)
Packaging
1g
Price
$1008
Updated
2021/12/16
Crysdot
Product number
CD12140008
Product name
Propane-1,3-diylbis(2-(4-chlorophenoxy)-2-methylpropanoate)
Purity
95+%
Packaging
1g
Price
$1186
Updated
2021/12/16
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simfibrate Chemical Properties,Usage,Production

Originator

Cholesorbin,Takeda,Japan,1971

Definition

ChEBI: Simfibrate is an organic molecular entity.

Manufacturing Process

A mixture of 22 grams of α-(p-chlorophenoxy)isobutyric acid, 3.8 grams of 1,3-propanediol, 0.5 gram of p-toluenesulfonic acid and 150 ml of xylene was refluxed. When the theoretically calculated amount of water had been removed, the xylene solution was washed with dilute aqueous sodium bicarbonate and then the xylene was distilled off. The residue was distilled under reduced pressure to give 11 grams (47% yield) of 1,3-propanediol bis[α-(p-chlorophenoxy)isobutyrate] boiling at 197° to 200°C/0.03 mm Hg.

Therapeutic Function

Antihyperlipidemic

simfibrate Preparation Products And Raw materials

Raw materials

Preparation Products

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simfibrate Suppliers

Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-87576359 15353716720
Email
1039@dideu.com
Country
China
ProdList
10009
Advantage
58
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Lanospharma Laboratories Co.,Ltd
Tel
--
Fax
--
Email
sales@lanospharma.com
Country
China
ProdList
6329
Advantage
56
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd
Tel
--
Fax
--
Email
sales@yickvic.com
Country
China
ProdList
6206
Advantage
58
Shanghai New Union Textra Import & Export Co., Ltd
Tel
--
Fax
--
Email
zhou@pharmchemical.com
Country
China
ProdList
2748
Advantage
60

14929-11-4, simfibrateRelated Search:


  • simfibrate
  • 1,3-Propanediol bis[2-(4-chlorophenoxy)-2-methylpropionate]
  • Bis[2-(4-chlorophenoxy)-2-methylpropanoic acid] 1,3-propanediyl
  • Cholesolvin
  • CLY-503
  • Sinfibrate
  • Propane-1,3-diyl bis(2-(4-chlorophenoxy)-2-methylpropanoate)
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 1,1'-(1,3-propanediyl) ester
  • simfibrate USP/EP/BP
  • 3-[2-(4-chlorophenoxy)-2-methylpropanoyl]oxypropyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 14929-11-4
  • C23H26Cl2O6