6,7-dimethoxyphthalide

Synthesis

Product Name: 6,7-dimethoxyphthalide
CAS No.: 569-31-3
Chemical Name: 6,7-dimethoxyphthalide
Synonyms: Opianyl;Meconine;NSC 35547;Meconic lactone;6,7-dimethoxyphthalide;Noscapine Impurity 4(Meconine);Meconin (1.0 mg/mL in Chloroform);6,7-dimethoxy-3H-2-benzofuran-1-one;6,7-DiMethoxy-3H-1-isobenzofuranone;6,7-dimethoxy-3H-isobenzofuran-1-one
CBNumber: CB4883065
Molecular Formula: C10H10O4
Formula Weight: 194.184
MOL File: 569-31-3.mol

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6,7-dimethoxyphthalide Property

Melting point:: 103℃
Boiling point:: 290.62°C (rough estimate)
Density: 1.2534 (rough estimate)
refractive index: 1.5430 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form: A crystalline solid
color: White to off-white
Water Solubility: 2.5g/L(25 ºC)

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Safety

HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 9001140
Product name: Meconin
Purity: ≥95%
Packaging: 5mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 9001140
Product name: Meconin
Purity: ≥95%
Packaging: 10mg
Price: $115
Updated: 2024/03/01

Cayman Chemical

Product number: 9001140
Product name: Meconin
Purity: ≥95%
Packaging: 50mg
Price: $468
Updated: 2024/03/01

Apolloscientific

Product number: OR928256
Product name: 6,7-Dimethoxyisobenzofuran-1(3H)-one
Purity: 98%
Packaging: 1g
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: 6419AJ
Product name: 6,7-Dimethoxyisobenzofuran-1(3H)-one
Packaging: 1g
Price: $284
Updated: 2021/12/16

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6,7-dimethoxyphthalide Chemical Properties,Usage,Production

Synthesis

Compound 7 (91.0 g, 0.5 mol), HCHO solution (81 g, 1.0 mol), HCl (80 g, 0.8 mol) and AcOH (200 g) were heated at 50~60 °C for 24 h to obtain a clear solution, which was then poured into cold water Chemicalbook (1kg). The resulting solid was collected by suction filtration, washed with water (60 g x 3), and dried at 50 °C to give crude cinnamon 8 (95 g) as a tan solid, which was purified by recrystallization from 90% MeOH/H2O (180 g) ) to obtain purified Meconin.

Chemical Properties

White Solid

Uses

A lactone of meconinic acid, extracted from opium. Meconin is a marker for illicit opiate use.

Definition

ChEBI: Meconine is a member of 2-benzofurans.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 3369, 1987 DOI: 10.1016/S0040-4039(00)95515-1

6,7-dimethoxyphthalide Preparation Products And Raw materials

Raw materials

Preparation Products

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6,7-dimethoxyphthalide Suppliers

Canada 1 China 52 India 4 United States 9 Global 66

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569-31-3, 6,7-dimethoxyphthalide Related Search:

Triamcinolone acetonide Azimsulfuron

6,7-dimethoxyphthalide

6,7-Dimethoxy-1(3H)-isobenzofuranone

6,7-Dimethoxyisobenzofuran-1(3H)-one

Meconic lactone

6,7-dimethoxy-3H-2-benzofuran-1-one

6,7-dimethoxy-3H-isobenzofuran-1-one

NSC 35547

Opianyl

Meconine

6,7-DiMethoxy-3H-1-isobenzofuranone

Noscapine Impurity 4(Meconine)

cyanoformic acid (phenylmethyl) ester

1(3H)-Isobenzofuranone, 6,7-dimethoxy-

Meconin (1.0 mg/mL in Chloroform)

Inhibitor,Endogenous Metabolite,Meconine,Meconin,inhibit

569-31-3

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals