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2-Bromo-5-chloro-1,3-difluorobenzene

Product Name
2-Bromo-5-chloro-1,3-difluorobenzene
CAS No.
883546-16-5
Chemical Name
2-Bromo-5-chloro-1,3-difluorobenzene
Synonyms
4-Chloro-2,6-difluorobromobenzene;3,5-Difluoro-4-bromo-chlorobenzene;1-Bromo-4-chloro-2,6-difluorobenzene;4-Bromo-1-chloro-3,5-difluorobenzene;2-Bromo-5-chloro-1,3-difluorobenzene;Benzene, 2-broMo-5-chloro-1,3-difluoro-;2-Bromo-5-Chloro-1,3-Difluorobenzene,>98%;4-Bromo-1-chloro-3,5-difluorobenzene ISO 9001:2015 REACH;1-Bromo-4-chloro-2,6-difluorobenzene [4-Bromo-3,5-difluorochlorobenzen
CBNumber
CB4971779
Molecular Formula
C6H2BrClF2
Formula Weight
227.43
MOL File
883546-16-5.mol
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2-Bromo-5-chloro-1,3-difluorobenzene Property

Boiling point:
176℃
Density 
1.805
Flash point:
60℃
storage temp. 
Sealed in dry,Room Temperature
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Safety

HazardClass 
IRRITANT
HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B683003
Product name
2-Bromo-5-chloro-1,3-difluorobenzene
Packaging
5g
Price
$195
Updated
2021/12/16
TRC
Product number
B683003
Product name
2-Bromo-5-chloro-1,3-difluorobenzene
Packaging
10g
Price
$275
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB83267
Product name
2-Bromo-5-chloro-1,3-difluorobenzene
Packaging
25g
Price
$440
Updated
2021/12/16
AK Scientific
Product number
J99584
Product name
2-Bromo-5-chloro-1,3-difluorobenzene
Packaging
25g
Price
$220
Updated
2021/12/16
Matrix Scientific
Product number
020558
Product name
2-Bromo-5-chloro-1,3-difluorobenzene
Purity
98%
Packaging
25g
Price
$222
Updated
2021/12/16
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2-Bromo-5-chloro-1,3-difluorobenzene Chemical Properties,Usage,Production

Synthesis

2-Bromo-5-chloro-1,3-difluorobenzene is synthesised using 4-bromo-3,5-difluoroaniline as a raw material by chemical reaction. The specific synthesis steps are as follows:
4-bromo-3,5-difluoroaniline (25.0g, 117mmol), copper chloride (I) (23.1g, 230mmol) and copper chloride (II) (47.0g, 350mmol) in acetonitrile (150 mL) mixed solution in, it was added dropwise acetonitrile (50 mL) solution of isoamyl nitrite (49.0mL, 350mmol) at room temperature. After stirring for 4 hours at room temperature the mixture solution, poured into 2N hydrochloric acid (300mL), diethyl - ether (200m And extracted with L × 3). The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to obtain a crude product of a brown solid. By purifying this product by a silica gel column (hexane), 2-bromo-5-chloro-1,3-difluorobenzene as a yellow oil (21.4 g, yield: 81%) was obtained.

Uses

2-Bromo-5-chloro-1,3-difluorobenzene is an organic intermediate that can be used to prepare other heterocyclic compounds as materials for organic electroluminescent devices.

2-Bromo-5-chloro-1,3-difluorobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-5-chloro-1,3-difluorobenzene Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 2-Bromo-5-chloro-1,3-difluorobenzene manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Bromo-1-chloro-3,5-difluorobenzene 883546-16-5
Price
US $101.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-28
Career Henan Chemical Co
Product
4-Bromo-1-chloro-3,5-difluorobenzene 883546-16-5
Price
US $3.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
200kg
Release date
2020-03-06