ChemicalBook > CAS DataBase List > Benzyl carbamate

Benzyl carbamate

Product Name
Benzyl carbamate
CAS No.
621-84-1
Chemical Name
Benzyl carbamate
Synonyms
Z-NH2;CARBAM;O-Benzylcarbamate;Benzyl aminoformate;N-CARBOBENZOXY-AMIDE;CarbaMyl Benzyl Ester;CARBAMIC ACID BENZYL ESTER;Z-AMIDE;Benzyl urethane;BENZYL CARBAMATE
CBNumber
CB5100170
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
621-84-1.mol
More
Less

Benzyl carbamate Property

Melting point:
86-89 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Powder or Flakes
pka
13.42±0.50(Predicted)
color 
Off-white to light beige
Water Solubility 
68.02g/L(37 ºC)
BRN 
1865635
InChIKey
PUJDIJCNWFYVJX-UHFFFAOYSA-N
CAS DataBase Reference
621-84-1(CAS DataBase Reference)
NIST Chemistry Reference
Carbamic acid, benzyl ester(621-84-1)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HS Code 
29242995
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B18200
Product name
Benzyl carbamate
Purity
99%
Packaging
25g
Price
$56.3
Updated
2024/03/01
Sigma-Aldrich
Product number
B18200
Product name
Benzyl carbamate
Purity
99%
Packaging
100g
Price
$127
Updated
2024/03/01
TCI Chemical
Product number
C0590
Product name
Benzyl Carbamate
Purity
>97.0%(N)
Packaging
25g
Price
$59
Updated
2024/03/01
TCI Chemical
Product number
C0590
Product name
Benzyl Carbamate
Purity
>97.0%(N)
Packaging
250g
Price
$437
Updated
2024/03/01
Alfa Aesar
Product number
A11569
Product name
Benzyl carbamate, 99%
Packaging
25g
Price
$36.65
Updated
2024/03/01
More
Less

Benzyl carbamate Chemical Properties,Usage,Production

Chemical Properties

Off-white to light beige powder or flakes, melting point 87-89 ℃. Insoluble in water, soluble in organic solvents such as benzene.

Uses

Benzyl carbamate is a reagent used for the nucleophilic introduction of an amino-protected group, Benzyl carbamates can be considered as a benzyloxycarbonyl (otherwise known as carbobenzyloxy, Cbz or Z) protecting group for amino groups. It was introduced as a versatile alternative to the ethoxy carbamate group in peptide synthesis.

Application

Benzyl carbamate is an intermediate in the synthesis of various pharmaceutical compounds. It can be also used as nondeuterated internal standards for the quantitative analysis of carisoprodol in blood.

Preparation

Benzyl carbamate is prepared by reacting benzyl chloroformate with ammonia. Benzyl chloroformate was slowly added to 5 times the volume of cold ammonia water (relative density 0.90) under vigorous stirring, the reaction mixture was placed at room temperature for 30 minutes, the precipitate was filtered out, washed with water and dried to obtain the finished product of benzyl carbamate.

Purification Methods

If it smells of NH3, then dry it in a vacuum desiccator and recrystallise it from 2 volumes of toluene and dry it in a vacuum desiccator again. It forms glistening plates from toluene, and can be recrystallised from H2O [Martell & Herbst J Org Chem 6 878 1941, Carter et al. Org Synth Coll Vol III 168 1955]. [Beilstein 6 IV 2278.]

Benzyl carbamate Preparation Products And Raw materials

Raw materials

Benzyl chloroformate

Preparation Products

More
Less

Benzyl carbamate Suppliers

Americas 1 Belgium 3 China 258 Europe 2 Germany 8 India 36 Japan 8 Switzerland 2 Ukraine 1 United Kingdom 11 United States 32 Global 362
Suzhou Vosun Biotech Co.,Ltd
Tel
0512-66569378-8002 66569378
Fax
0512-82177265
Email
info@vosunchemical.com
Country
China
ProdList
614
Advantage
58
Hunan Caiya Biological Technology Co., Ltd
Tel
15580017485
Email
2036676503@qq.com
Country
China
ProdList
88
Advantage
58
Shanghai Hobor Chemical Co., Ltd
Tel
21-21-61026752 13918007836
Fax
021-51685238
Email
sales@hoborchem.com
Country
China
ProdList
402
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820 13031183356
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1392
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
498
Advantage
75
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17987
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3206
Advantage
55
Sci General Material & Chemical Ltd
Tel
21-58388037 13472507714
Fax
0086-21-56829747 Company QQ: 1589045147
Email
1589045147@qq.com
Country
China
ProdList
673
Advantage
55
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Medpep Co., Ltd
Tel
021-65566949 13901795941
Fax
86-21-51861665
Email
market@medpep.com
Country
China
ProdList
176
Advantage
66
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
15928766785 15928766785
Fax
QQ961458712
Email
wupengcheng@astatech.cn
Country
China
ProdList
1995
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
ShangHai Zexin Chemical Technology Co., Ltd.
Tel
021-60136491 15901897992
Fax
021-60136492
Country
China
ProdList
455
Advantage
55
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Shanghai Hongbang Pharmaceutical Co., Ltd.
Tel
021-64975436 18917636693
Fax
021-24280809
Email
1377976036@qq.com
Country
China
ProdList
297
Advantage
55
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3123
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3993
Advantage
60
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3998
Advantage
58
More
Less

View Lastest Price from Benzyl carbamate manufacturers

Hebei Duling International Trade Co. LTD
Product
Benzyl carbamate 621-84-1
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2022-10-31
Hebei Yanxi Chemical Co., Ltd.
Product
Benzyl carbamate 621-84-1
Price
US $50.00-8.50/kg
Min. Order
1kg
Purity
0.99
Supply Ability
30 tons
Release date
2023-09-07
Hebei Guanlang Biotechnology Co., Ltd.
Product
Benzyl carbamate 621-84-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-20

621-84-1, Benzyl carbamateRelated Search:

Benzyl alcohol Chlorpropham Benzyl benzoate Benzyl formate Benzyl chloroformate POLYURETHANE Carbobenzoxyhydrazide 4-Nitrobenzyl chloroformate AMINOGUANIDINE HEMISULFATE Aminoguanidine bicarbonate Sulfamic acid 2,6-DI-TERT-BUTYLNAPHTHALENE SULFONIC ACID SODIUM SALT Trimethylstearylammonium Chloride 2,3-Butanediol Ethylene Glycol Dibutyl Ether Ethylene dimethacrylate 2,2-Diethoxyethylamine N-Benzyloxycarbonyl-L-asparagine

  • N-CARBOBENZOXY-AMIDE
  • O-Benzylcarbamate
  • Z-AMIDE
  • Z-NH2
  • BENZYLOXYCARBONYL AMIDE
  • BENZYL CARBAMATE
  • CARBAMIC ACID BENZYL ESTER
  • CARBAM
  • Benzylcarbamate (Z-NH2)
  • Carbamic acid benzyl ester~Z-NH_2
  • Benzyl carbamate,98%
  • Phenylmethyl carbamate
  • Benzyl urethane
  • Benzyloxycarbonylamine
  • Benzyl carbaMate, 98% 25GR
  • Z-NH2 Benzyl carbamate
  • Benzyl aminoformate
  • CarbaMyl Benzyl Ester
  • Benzyl carbaMate 99%
  • Benzyl Carbamate &gt
  • Benzyl carbamate ISO 9001：2015 REACH
  • Carbobenzoxyamide
  • Benzylcarbamate(BC)
  • TIANFUCHEM--621-84-1--Benzyl carbamate factory price
  • 621-84-1
  • H2NCOOCH2C6H5
  • NH2COOCH2C6H5
  • H2NCO2CH2C6H5
  • Protected Amines
  • Nitrogen Compounds
  • Organic Building Blocks
  • Building Blocks
  • Building Blocks
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines
  • Heterocycles
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amines
  • bc0001