ChemicalBook > CAS DataBase List > 6-BROMO-2,4-DICHLOROQUINAZOLINE

6-BROMO-2,4-DICHLOROQUINAZOLINE

Product Name
6-BROMO-2,4-DICHLOROQUINAZOLINE
CAS No.
102393-82-8
Chemical Name
6-BROMO-2,4-DICHLOROQUINAZOLINE
Synonyms
4-dichloroquinazoline;6-Bromo-2,4-dichloroquina...;6-broMo-2,4-dichlroquinazoline;2,4-Dichloro-6-broMoquinazoline;6-BROMO-2,4-DICHLOROQUINAZOLINE;Quinazoline, 6-bromo-2,4-dichloro-;6-Bromo-2,4-dichloroquinazoline,97%
CBNumber
CB51012890
Molecular Formula
C8H3BrCl2N2
Formula Weight
277.93
MOL File
102393-82-8.mol
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6-BROMO-2,4-DICHLOROQUINAZOLINE Property

Boiling point:
330.2±24.0 °C(Predicted)
Density 
1.851±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
pka
-1.19±0.30(Predicted)
form 
Solid
color 
Off-white
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C8H3BrCl2N2/c9-4-1-2-6-5(3-4)7(10)13-8(11)12-6/h1-3H
InChIKey
LBAYOWRVZAKPLS-UHFFFAOYSA-N
SMILES
N1=C2C(C=C(Br)C=C2)=C(Cl)N=C1Cl
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H63603
Product name
6-Bromo-2,4-dichloroquinazoline, 97%
Packaging
1g
Price
$148
Updated
2023/06/20
Alfa Aesar
Product number
H63603
Product name
6-Bromo-2,4-dichloroquinazoline, 97%
Packaging
5g
Price
$733
Updated
2023/06/20
Alfa Aesar
Product number
H63603
Product name
6-Bromo-2,4-dichloroquinazoline, 97%
Packaging
250mg
Price
$42.3
Updated
2021/12/16
TRC
Product number
B691208
Product name
6-Bromo-2,4-dichloroquinazoline
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
B691208
Product name
6-Bromo-2,4-dichloroquinazoline
Packaging
500mg
Price
$65
Updated
2021/12/16
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6-BROMO-2,4-DICHLOROQUINAZOLINE Chemical Properties,Usage,Production

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

The synthesis of 6-BROMO-2,4-DICHLOROQUINAZOLINE is as follows:BTC (0.65 g, 2.2 mmol in 6mL of PhCl) was added to astirred solution of tris(4-methoxyphenyl)phosphine oxide 3d(0.33 g, 0.9 mmol in 5mL PhCl) dropwise in a round botttomflask placed on an ice bath. After complete addition,the mixture was stirred for 30 min at room temperature.Then isatin-3-oximes (3 mmol) were added, and the mixturewas heated to 120 C until completion of the reaction(followed by TLC, n-hexane/ethyl acetate 10:1). Aftercooling, the mixture was then poured into 50mL ice waterand extracted with ethyl acetate (320 mL). The organiclayer was dried over anhydrous Na2SO4 and concentrated invacuo. The crude product was purified over column chromatography(n-hexane/ethyl acetate 10:1) to afford thepure produce 2,4-dichloroquinazolins. Tris(4-methoxyphenyl)phosphine oxide 3d was recovered by column chromatography(n-hexane/ethyl acetate 1:1).

6-BROMO-2,4-DICHLOROQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2,4-DICHLOROQUINAZOLINE Suppliers

China 139 Germany 1 India 1 United Kingdom 2 United States 15 Global 158
Pure Chemistry Scientific Inc.
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View Lastest Price from 6-BROMO-2,4-DICHLOROQUINAZOLINE manufacturers

Career Henan Chemical Co
Product
6-BROMO-2,4-DICHLOROQUINAZOLINE 102393-82-8
Price
US $0.01/KG
Min. Order
1KG
Purity
98%； 99%
Supply Ability
1kg; 5kg; 10kg；25kg
Release date
2020-01-07

102393-82-8, 6-BROMO-2,4-DICHLOROQUINAZOLINERelated Search:

6-bromo-2,3-dichloroquinoxaline 6-Bromo-2,3-Dihydroquinolin-4(1H)-One 8-BROMO-2,4-DICHLOROQUINAZOLINE 2,4-Dichloroquinazoline 6-Bromo-2-chloroquinazoline 6-BROMO-2,4-DICHLOROQUINAZOLINE 6-Bromo-4-chloroquinazoline

  • 6-BROMO-2,4-DICHLOROQUINAZOLINE
  • 6-Bromo-2,4-dichloroquina...
  • 2,4-Dichloro-6-broMoquinazoline
  • 4-dichloroquinazoline
  • 6-broMo-2,4-dichlroquinazoline
  • Quinazoline, 6-bromo-2,4-dichloro-
  • 6-Bromo-2,4-dichloroquinazoline,97%
  • 102393-82-8
  • C8H3BrCl2N2
  • CHIRAL CHEMICALS