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A-METHYL-L-TRYPTOPHAN

Product Name
A-METHYL-L-TRYPTOPHAN
CAS No.
153-91-3
Chemical Name
A-METHYL-L-TRYPTOPHAN
Synonyms
α-Me-DL-Trp;α-Me-DL-Trp-OH;Dl-2-Me-Trp-OH;H-DL-(ME)TRP-OH;H-α-Me-DL-Trp-OH;H-a-Me-DL-Trp-OH;α-Methyltryptophan;H-ALPHA-ME-DL-TRP-OH;Tryptophan,a-methyl-;A-METHYL-L-TRYPTOPHAN
CBNumber
CB5105786
Molecular Formula
C12H14N2O2
Formula Weight
218.26
MOL File
153-91-3.mol
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A-METHYL-L-TRYPTOPHAN Property

Melting point:
234 °C(Solv: ethanol, 60% (64-17-5))
Boiling point:
444.0±35.0 °C(Predicted)
Density 
1.314±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
crystalline
pka
2.34±0.10(Predicted)
color 
light yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M8377
Product name
α-Methyl-DL-tryptophan
Purity
crystalline
Packaging
100mg
Price
$83.4
Updated
2025/07/31
Sigma-Aldrich
Product number
M8377
Product name
α-Methyl-DL-tryptophan
Purity
crystalline
Packaging
1g
Price
$402
Updated
2025/07/31
Sigma-Aldrich
Product number
M8377
Product name
α-Methyl-DL-tryptophan
Purity
crystalline
Packaging
250mg
Price
$135
Updated
2025/07/31
Usbiological
Product number
283812
Product name
DL-alpha-Methyltryptophan
Packaging
500mg
Price
$333
Updated
2021/12/16
TRC
Product number
M327120
Product name
α-Methyl-DL-tryptophan
Packaging
100mg
Price
$65
Updated
2021/12/16
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A-METHYL-L-TRYPTOPHAN Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

α-methyl-DL-tryptophan is used as a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer. It is also a substrate or non-transported inhibitor of the amino acid transporter PAT2 (slc36a2).

Biochem/physiol Actions

α-methyl-DL-tryptophan is a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer.

in vivo

α-Methyl-DL-tryptophan (α-MT) (2 mg/mL; administered in drinking water; continuously administered; throughout the experimental period) inhibits tumor growth in BALB/c nude mice inoculated with ZR-75-1 cells[1].
α-Methyl-DL-tryptophan (1 mg/mL; administered in drinking water; continuously administered; for 1 week) reduces body weight in wild-type mice on a high-fat diet[2].

Animal Model:BALB/c nude mice (female) inoculated with ZR-75-1 cells[1]
Dosage:2 mg/mL
Administration:Administered in drinking water
Result:Reduced the growth of ZR-75-1 cells. Tumor size was significantly smaller than that in the control group.
Animal Model:Wild-type C57BL/6 male mice fed a high-fat diet[2]
Dosage:1 mg/mL
Administration:Administered in drinking water, continuously for 1weeks
Result:Led to a decrease in body weight.

A-METHYL-L-TRYPTOPHAN Preparation Products And Raw materials

Raw materials

Preparation Products

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A-METHYL-L-TRYPTOPHAN Suppliers

Canada 1 China 70 Germany 1 India 2 Japan 1 Switzerland 3 United Kingdom 1 United States 10 Global 89
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from A-METHYL-L-TRYPTOPHAN manufacturers

Honest Joy Holdings Limited
Product
H-a-Me-DL-Trp-OH 153-91-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99.1%
Supply Ability
100 tons
Release date
2022-02-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
A-METHYL-L-TRYPTOPHAN 153-91-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

153-91-3, A-METHYL-L-TRYPTOPHANRelated Search:

ALPHA-METHYL-L-TRYPTOPHAN,α-Methyl-(S)-tryptophan H-VAL-PNA HCL L-Valine benzyl ester hydrochloride H-VAL-ILE-OH H-VAL-ALA-OH ALPHA-METHYL-L-VALINE HYDROCHLORIDE H-VAL-VAL-OH L-VALINE TERT-BUTYL ESTER HYDROCHLORIDE L-Valine methyl ester hydrochloride L-Valine benzyl ester 4-toluenesulfonate ALPHA-METHYL-DL-HISTIDINE DIHYDROCHLORIDE H-α-Me-Tyr(tBu)-OH H-VAL-TYR-OH H-VAL-NH2 HCL H-ALPHA-ME-D-VAL-OH Dipeptide-2 5-METHYL-DL-TRYPTOPHAN DL-Tryptophan

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  • DL-2-METHYL-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID
  • DL-ALPHA-METHYLTRYPTOPHAN
  • H-ALPHA-ME-DL-TRP-OH
  • H-DL-(ME)TRP-OH
  • A-methyl-dl-tryptophan
  • H-a-Me-DL-Trp-OH
  • H-α-Me-DL-Trp-OH
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  • 2-AMino-3-(1H-indol-3-yl)-2-Methylpropanoic acid
  • DL-α-Methyltryptophan
  • α-Me-DL-Trp
  • DL-α-Methyltryptophan≥ 99% (HPLC)
  • α-Me-DL-Trp-OH
  • Dl-2-Me-Trp-OH
  • Tryptophan,a-methyl-
  • α-Methyl-DL-tryptophan
  • A-METHYL-L-TRYPTOPHAN USP/EP/BP
  • α-Methyltryptophan
  • Tryptophan, α-methyl-
  • α-Methyl-<sc>DL</sc>-tryptophan
  • alpha-Methyl-DL-tryptophan crystalline
  • 153-91-3
  • Biochemicals and Reagents
  • BioChemical
  • Amino Acids and Peptides
  • I - Z
  • Modified Amino Acids
  • Amino Acids
  • I - Z
  • Modified Amino Acids