4-Nitrosalicylic acid Property

Melting point:

235-239 °C (lit.)

Boiling point:

316.77°C (rough estimate)

Density 

1.6074 (rough estimate)

refractive index 

1.6280 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

Solid or Crystalline Powder

pka

2.11±0.13(Predicted)

color 

White to pale brown

InChIKey

UKWUOTZGXIZAJC-UHFFFAOYSA-N

CAS DataBase Reference

619-19-2(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 2-hydroxy-4-nitro- (619-19-2)

Safety

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

VO5300100

HS Code 

29182900

Toxicity

LD50 orl-mus: 650 mg/kg ZNTFA2 6B,183,51

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-Nitrosalicylic acid Chemical Properties,Usage,Production

Chemical Properties

White to yellow crystalline powder

Uses

4-Nitrosalicylic Acid is a metabolite in the degradation pathway of 2-chloro-4-nitrobenzoic acid by acinetobacter strain RKJ12.

Uses

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General Description

2-Hydroxy-4-nitrobenzoic acid is metabolized to 2,4-dihydroxybenzoic acid (2,4-DHBA) by a mono-oxygenase with the concomitant release of chloride and nitrite ions.

Safety Profile

Poison by intraperitoneal route.Moderately toxic by ingestion. When heated todecomposition it emits toxic vapors of NOx.