2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde
- Product Name
- 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde
- CAS No.
- 33985-71-6
- Chemical Name
- 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde
- Synonyms
- 9-uronidine;9-Formyljulolidine;Julolidine Aldehyde;2,3,6,7-Tetrahydro-1;9-Julolidinecarboxaldehyde;9-Julolidinecarboxaldehyde>2,3,3a,4,5,6-Hexahydro-3a-aza-1H-phenalene-8-carbaldehyde;1,2,3,4,5,6-Hexahydro-3a-aza-3aH-phenalene-8-carbaldehyde;2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carbaldehyde;1,2,3,5,6,7-Hexahydropyrido[3,2,1-ij]quinoline-9-carbaldehyde
- CBNumber
- CB51074241
- Molecular Formula
- C13H15NO
- Formula Weight
- 201.26
- MOL File
- 33985-71-6.mol
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde Property
- Melting point:
- 83 °C
- Boiling point:
- 404.8±44.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.15±0.20(Predicted)
- color
- Light orange to Yellow to Green
- InChI
- InChI=1S/C13H15NO/c15-9-10-7-11-3-1-5-14-6-2-4-12(8-10)13(11)14/h7-9H,1-6H2
- InChIKey
- XIIVBURSIWWDEO-UHFFFAOYSA-N
- SMILES
- C12=CC(C=O)=CC3=C1N(CCC3)CCC2
- EPA Substance Registry System
- 1H,5H-Benzo[ij]quinolizine-9-carboxaldehyde, 2,3,6,7-tetrahydro- (33985-71-6)
Safety
- RTECS
- DK1480000
- HS Code
- 2933.49.7000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- J0008
- Product name
- 9-Julolidinecarboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $238
- Updated
- 2025/07/31
- Product number
- 43165
- Product name
- 9-Julolidinecarboxaldehyde,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 1G
- Price
- $260
- Updated
- 2021/12/16
- Product number
- CHM0308711
- Product name
- 9-JULOLIDINE CARBOXALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.81
- Updated
- 2021/12/16
- Product number
- 081750
- Product name
- 2,3,6,7-Tetrahydro-1H,5H-pyrido-[3,2,1-ij]quinoline-9-carbaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $598
- Updated
- 2021/12/16
- Product number
- 0859AE
- Product name
- 9-Julolidinecarboxaldehyde
- Packaging
- 5g
- Price
- $605
- Updated
- 2021/12/16
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde Chemical Properties,Usage,Production
Description
9-Julolidinecarboxaldehyde is a fluorescent probe.
Synthesis
479-59-4
68-12-2
33985-71-6
Julolidine (0.5 g, 2.89 mmol), N,N-dimethylformamide (0.255 g, 3.49 mmol), and phosphorous trichloride (0.535 g, 3.49 mmol) were dissolved in dichloromethane (15 mL), and the mixture was stirred for 4 h at room temperature under argon protection. The color of the solution changed to green during the reaction and the progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction was quenched with water and the crude product was subsequently extracted with 2 M sodium hydroxide solution and ether. The organic phase was washed twice with water, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography with 40%-50% ether/hexane as eluent to give 0.48 g (83.08% yield) of 1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline-9-carboxaldehyde as a light-yellow solid (up to 92% when 1.5 g of julonidine was used). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 9.597 (s, 1H), 7.29 (s, 1H), 3.308 (t, J = 57 Hz, 4H), 2.787 (t, J = 62 Hz, 4H), 2.002-1.92 (m, J = 63 Hz, 4H).
References
[1] Tetrahedron, 2007, vol. 63, # 1, p. 103 - 114
[2] Organic Preparations and Procedures International, 2001, vol. 33, # 6, p. 603 - 613
[3] Journal of Nanoscience and Nanotechnology, 2015, vol. 15, # 11, p. 8813 - 8819
[4] Chemistry - A European Journal, 2010, vol. 16, # 30, p. 9257 - 9263
[5] Chemical Communications, 2014, vol. 50, # 78, p. 11507 - 11510
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde manufacturers
- Product
- 9-julolidinecarboxaldehyde 33985-71-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons
- Release date
- 2020-02-14