2-Fluoro-4-(methylsulfonyl)aniline

Product Name: 2-Fluoro-4-(methylsulfonyl)aniline
CAS No.: 832755-13-2
Chemical Name: 2-Fluoro-4-(methylsulfonyl)aniline
Synonyms: 2-fluoro-4-Methanesulfonylaniline;2-Fluoro-4-(methylsulfonyl)aniline;2-Fluoro-4-(methylsulfonyl)phenylamine;2-fluoro-4-(Methylsulfonyl)benzenaMine;4-Amino-3-fluorophenyl methyl sulphone;2-Fluoro-4-(methylsulphonyl)aniline 99%;Benzenamine, 2-fluoro-4-(methylsulfonyl)-;1-Amino-2-fluoro-4-(methylsulphonyl)benzene
CBNumber: CB51096458
Molecular Formula: C7H8FNO2S
Formula Weight: 189.21
MOL File: 832755-13-2.mol

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2-Fluoro-4-(methylsulfonyl)aniline Property

Melting point:: 145-147°C
Boiling point:: 371.0±42.0 °C(Predicted)
Density: 1.374±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
form: crystalline solid
pka: -0.04±0.10(Predicted)
color: Faint brown

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F598035
Product name: 2-Fluoro-4-(methylsulfonyl)aniline
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC0964
Product name: 2-Fluoro-4-(methylsulphonyl)aniline
Purity: 99%
Packaging: 5g
Price: $54
Updated: 2021/12/16

Matrix Scientific

Product number: 016098
Product name: 2-Fluoro-4-(methylsulfonyl)aniline
Purity: 98%
Packaging: 5g
Price: $74
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8669-3-X1
Product name: 2-Fluoro-4-(methylsulfonyl)aniline
Purity: 99%
Packaging: 5G
Price: $85
Updated: 2021/12/16

Matrix Scientific

Product number: 016098
Product name: 2-Fluoro-4-(methylsulfonyl)aniline
Purity: 98%
Packaging: 25g
Price: $206
Updated: 2021/12/16

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2-Fluoro-4-(methylsulfonyl)aniline Chemical Properties,Usage,Production

Synthesis

29632-74-4

20277-69-4

832755-13-2

The general procedure for the synthesis of 2-fluoro-4-methylsulfinylaniline from 2-fluoro-4-iodoaniline and sodium methanesulfinic acid was as follows: firstly, to a solution of 2-fluoro-4-iodoaniline (206.8 g, 872.3 mmol) in DMSO (1.1 L) was added, in order, copper(II)-benzene trifluoromethanesulfonate complex (30.74 g, 61.1 mmol), sodium methanesulfinic acid ( 106.9 g, 1.047 mol) and N,N'-dimethylethylenediamine (13.2 mL, 122 mmol). Subsequently, the reaction vessel was placed in an oil bath preheated to 120°C and the reaction mixture was stirred overnight. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with water and extracted several times with EtOAc. The organic extracts were combined, washed five times with brine, dried over MgSO4 and concentrated under reduced pressure to remove the solvent. The resulting purple solid was washed with diisopropyl ether and then dried in a vacuum oven at room temperature to constant weight to give 151.5 g of dark purple solid in 92% yield. The product was identified by 1H NMR (DMSO-d6): δ 7.41 (d, 1H, J = 8.5 Hz), 6.87 (t, 1H, J = 8.6 Hz), 6.19 (s, 2H), 3.10 (s, 3H); MS m/z 190.3 (M+).

References

[1] Patent: WO2005/121121, 2005, A2. Location in patent: Page/Page column 148-149

2-Fluoro-4-(methylsulfonyl)aniline Preparation Products And Raw materials

Raw materials

4-Bromo-2-fluoroaniline Cuprous iodide L-Proline Sodium methanesulfinate

Preparation Products

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2-Fluoro-4-(methylsulfonyl)aniline Suppliers

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View Lastest Price from 2-Fluoro-4-(methylsulfonyl)aniline manufacturers

Career Henan Chemical Co

Product: 2-Fluoro-4-(methylsulfonyl)aniline 832755-13-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-14

832755-13-2, 2-Fluoro-4-(methylsulfonyl)anilineRelated Search:

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2-Fluoro-4-(methylsulfonyl)phenylamine

2-Fluoro-4-(methylsulfonyl)aniline

2-Fluoro-4-(methylsulphonyl)aniline 99%

4-Amino-3-fluorophenyl methyl sulphone

2-fluoro-4-(Methylsulfonyl)benzenaMine

2-fluoro-4-Methanesulfonylaniline

1-Amino-2-fluoro-4-(methylsulphonyl)benzene

Benzenamine, 2-fluoro-4-(methylsulfonyl)-

832755-13-2

Benzene series

API intermediates

Amines and Anilines

Boron, Nitrile, Thio,& TM-Cpds