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Flumexadol

Product Name
Flumexadol
CAS No.
30914-89-7
Chemical Name
Flumexadol
Synonyms
1841CERM;CERM-1841;Flumexadol;2-(α,α,α-Trifluoro-m-tolyl)morpholine;2-[3-(Trifluoromethyl)phenyl]morpholine;Morpholine, 2-[3-(trifluoromethyl)phenyl]-
CBNumber
CB51178778
Molecular Formula
C11H12F3NO
Formula Weight
231.21
MOL File
30914-89-7.mol
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Flumexadol Property

Boiling point:
132 °C(Press: 10 Torr)
Density 
1.2081 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (432.51 mM)
pka
8.41±0.40(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
T900660
Product name
2-[3-(Trifluoromethyl)phenyl]morpholine
Packaging
10mg
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-0109485
Product name
Flumexadol
Purity
98.87%
Packaging
10mg
Price
$115
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0126047
Product name
2-[3-(TRIFLUOROMETHYL)PHENYL]-MORPHOLINE
Purity
95.00%
Packaging
1G
Price
$787.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0126047
Product name
2-[3-(TRIFLUOROMETHYL)PHENYL]-MORPHOLINE
Purity
95.00%
Packaging
2.5G
Price
$1663.02
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0126047
Product name
2-[3-(TRIFLUOROMETHYL)PHENYL]-MORPHOLINE
Purity
95.00%
Packaging
5G
Price
$2223.51
Updated
2021/12/16
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Flumexadol Chemical Properties,Usage,Production

Biological Activity

Flumexadol is an orally active non-narcotic analgesic. It is a selective and affinity agonist of the 5-HT2C receptor with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, 40-fold more selective than the 5-HT2A receptor.

in vivo

In rats and dogs dosed with 14 C-Flumexadol (CERM1841), the 14 C is excreted in the urine. The 14 C eliminated in the faeces of dog is significantly higher than for rat. Conjugated metabolites, mostly glucuronides, accounted for the greater part of the urinary radioactivity in both species. Biotransformation products are predominantly acids in both species, follows by significant amounts of basic metabolites, with very little neutral substances. The major urinary metabolite in rats is 3-trifluoromethylbenzoic acid and 3-trifluoromethylhipuric acid. In the dog it is 3-trifluoromethylmandelic acid in addition to the benzoic acid and its conjugate. The basic products identified in the urine of both species are unchanged drug and 1-amino-2-hydroxy-2-(3-trifluoromethylphenyl)ethane, with the first predominating.

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target

5-HT 2C Receptor

25 nM (Ki)

Flumexadol Preparation Products And Raw materials

Raw materials

Preparation Products

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Flumexadol Suppliers

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30914-89-7, FlumexadolRelated Search:


  • Flumexadol
  • 1841CERM
  • 2-(α,α,α-Trifluoro-m-tolyl)morpholine
  • 2-[3-(Trifluoromethyl)phenyl]morpholine
  • CERM-1841
  • Morpholine, 2-[3-(trifluoromethyl)phenyl]-
  • 30914-89-7