2-(TRIFLUOROMETHYL)NICOTINALDEHYDE

Product Name: 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE
CAS No.: 116308-35-1
Chemical Name: 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE
Synonyms: 2-(Trifluoromwthyl)nicotinaldehyde;2-(TRIFLUOROMETHYL)NICOTINALDEHYDE;2-Trifluoromethyl-pyridine-3-carbaldehyde;2-trifluoromethyl-3-pyridine formaldehyde;2-(trifluoromethyl)-3-pyridinecarboxaldehyde;2-(Trifluoromethyl)pyridine-3-carBoxaldehyde;3-Pyridinecarboxaldehyde,2-(trifluoromethyl)-
CBNumber: CB5121825
Molecular Formula: C7H4F3NO
Formula Weight: 175.11
MOL File: 116308-35-1.mol

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2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Property

Boiling point:: 207.9±40.0 °C(Predicted)
Density: 1.369±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.25±0.22(Predicted)
Appearance: Colorless to light yellow Liquid

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Safety

Hazard Codes: T
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T791768
Product name: 2-(Trifluoromethyl)nicotinaldehyde
Packaging: 100mg
Price: $175
Updated: 2021/12/16

Apolloscientific

Product number: PC3733
Product name: 2-(Trifluoromethyl)nicotinaldehyde
Packaging: 250mg
Price: $225
Updated: 2021/12/16

Matrix Scientific

Product number: 119998
Product name: 2-(Trifluoromethyl)nicotinaldehyde
Purity: 95+%
Packaging: 250mg
Price: $317
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H15-3-X1
Product name: 2-(Trifluoromethyl)nicotinaldehyde
Packaging: 250mg
Price: $360
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0010445
Product name: 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE
Purity: 95.00%
Packaging: 5MG
Price: $503.43
Updated: 2021/12/16

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2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Chemical Properties,Usage,Production

Synthesis

131747-57-4

116308-35-1

(2-Trifluoromethyl-pyridin-3-yl)-methanol (0.05 g, 0.28 mmol) was used as starting material and dissolved in anhydrous dichloromethane (10 mL). Subsequently, manganese dioxide (0.7 g, 8.0 mmol) was added to the solution. The reaction mixture was stirred under reflux conditions for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered through diatomaceous earth. The filtrate was concentrated by rotary evaporator to afford the target product 2-(trifluoromethyl)pyridine-3-carboxaldehyde as a yellow oil (0.035 g, 71% yield), which could be used in subsequent steps without further purification. The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3) and mass spectrometry (ESI+): 1H-NMR δ 10.40 (s, 1H), 8.83 (d, J = 4.7 Hz, 1H), 8.37 (d, J = 8.0 Hz, 1H), 7.63 (dd, J = 8.0 and 4.7 Hz, 1H); MS (ESI+): m/ z (M + H)+ = 176.

References

[1] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 17, p. 5352 - 5359
[3] Synthesis, 2005, # 16, p. 2751 - 2757
[4] Patent: WO2012/87519, 2012, A1. Location in patent: Page/Page column 123

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Suppliers

China 71 India 2 United Kingdom 2 United States 11 Global 86

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View Lastest Price from 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE manufacturers

Career Henan Chemical Co

Product: 2-(Trifluoromethyl)nicotinaldehyde 116308-35-1
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg,10kg,100kg
Release date: 2020-01-09

116308-35-1, 2-(TRIFLUOROMETHYL)NICOTINALDEHYDERelated Search:

6-(TRIFLUOROMETHYL)NICOTINALDEHYDE,6-(Trifluoromethyl)nicotinaldehyde 97% 4-(TRIFLUOROMETHYL)NICOTINALDEHYDE 2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINALDEHYDE 2-CHLORO-6-(TRIFLUOROMETHYL)NICOTINALDEHYDE 2-CHLORO-4-(TRIFLUOROMETHYL)NICOTINALDEHYDE ETHYL 2-CHLORO-3-CYANO-6-(TRIFLUOROMETHYL)-PYRIDINE-5-CARBOXYLATE 1,8-Naphthyridine-3-carboxylicacid,2-(trifluoromethyl)-,ethylester(9CI) 2-(TRIFLUOROMETHYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID BUTTPARK 82\12-87 5-OXO-N-(2-PYRIDINYLMETHYL)-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-N-(3-PYRIDINYLMETHYL)-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-N-PHENYL-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-2-(TRIFLUOROMETHYL)-N-[3-(TRIFLUOROMETHYL)PHENYL]-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-(4-CHLOROBENZYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-(4-CHLOROPHENYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-ALLYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 6-HYDROXY-5-(2-HYDROXYBENZOYL)-2-(TRIFLUOROMETHYL)NICOTINIC ACID N-BENZYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE

2-(Trifluoromwthyl)nicotinaldehyde

3-Pyridinecarboxaldehyde,2-(trifluoromethyl)-

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE

2-(Trifluoromethyl)pyridine-3-carBoxaldehyde

2-Trifluoromethyl-pyridine-3-carbaldehyde

2-(trifluoromethyl)-3-pyridinecarboxaldehyde

2-trifluoromethyl-3-pyridine formaldehyde

116308-35-1

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