3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-

Product Name: 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-
CAS No.: 735273-33-3
Chemical Name: 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-
Synonyms: α-Glucosidase-IN-9;3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-
CBNumber: CB512745758
Molecular Formula: C19H12N4OS
Formula Weight: 344.39
MOL File: 735273-33-3.mol

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3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Property

Melting point:: 314 °C(Solv: acetonitrile (75-05-8))
Boiling point:: 630.5±55.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
pka: 6.65±0.15(Predicted)

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Hazard and Precautionary Statements (GHS)

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3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Chemical Properties,Usage,Production

Uses

α-Glucosidase-IN-9 (compound 7) is a potent α-glucosidase inhibitor, with an IC50 of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research[1].

IC 50

Glucosidase

References

[1] Ali M, et al. Synthesis, in vitro and in silico screening of 2-amino-4-aryl-6-(phenylthio) pyridine-3,5-dicarbonitriles as novel α-glucosidase inhibitors. Bioorg Chem. 2020 Jul;100:103879. DOI:10.1016/j.bioorg.2020.103879

3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Suppliers

China 2 United States 1 Global 3

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 8011
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TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29357
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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
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735273-33-3, 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-Related Search:

α-Glucosidase-IN-29 KRN7000 α-galactosidase 5H-Indeno[1,2-b]pyridin-5-one, 6,7-dimethoxy-4-methyl- Benzoic acid, 4-[2-[(Z)-(4,5-dihydro-6-methyl-3,4-dioxofuro[3,4-c]pyridin-1(3H)-ylidene)methyl]-5-(hydroxymethyl)-1H-pyrrol-1-yl]-, ethyl ester Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)- ALPHA-GUANIDINOGLUTARIC ACID 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-bromo-3,5-dimethoxyphenyl)-6-(phenylthio)-

3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)-

α-Glucosidase-IN-9

735273-33-3