quinaldopeptin
- Product Name
- quinaldopeptin
- CAS No.
- 130743-07-6
- Chemical Name
- quinaldopeptin
- Synonyms
- quinaldopeptin;BMY 28662, BU 3845T;Quinaldopeptin (9CI)
- CBNumber
- CB51318925
- Molecular Formula
- C62H78N14O14
- Formula Weight
- 1243.38
- MOL File
- 130743-07-6.mol
quinaldopeptin Property
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: slightly soluble; Methanol: slightly soluble
- form
- Yellow powder.
- pka
- 6.91±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- 28167
- Product name
- Quinaldopeptin
- Packaging
- 500μg
- Price
- $401
- Updated
- 2024/03/01
- Product number
- 28167
- Product name
- Quinaldopeptin
- Packaging
- 2.5mg
- Price
- $1502
- Updated
- 2024/03/01
- Product number
- Q0965
- Product name
- Quinaldopeptin
- Packaging
- 500ug
- Price
- $582
- Updated
- 2021/12/16
- Product number
- API0019178
- Product name
- QUINALDOPEPTIN
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $646
- Updated
- 2021/12/16
quinaldopeptin Chemical Properties,Usage,Production
Description
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Uses
Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumour, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.
Uses
Quinaldopeptin is a bis-intercalating cyclic peptide antibiotic.
quinaldopeptin Preparation Products And Raw materials
Raw materials
Preparation Products
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