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quinaldopeptin

Product Name
quinaldopeptin
CAS No.
130743-07-6
Chemical Name
quinaldopeptin
Synonyms
quinaldopeptin;BMY 28662, BU 3845T;Quinaldopeptin (9CI)
CBNumber
CB51318925
Molecular Formula
C62H78N14O14
Formula Weight
1243.38
MOL File
130743-07-6.mol
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quinaldopeptin Property

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: slightly soluble; Methanol: slightly soluble
form 
Yellow powder.
pka
6.91±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28167
Product name
Quinaldopeptin
Packaging
500μg
Price
$401
Updated
2024/03/01
Cayman Chemical
Product number
28167
Product name
Quinaldopeptin
Packaging
2.5mg
Price
$1502
Updated
2024/03/01
Usbiological
Product number
Q0965
Product name
Quinaldopeptin
Packaging
500ug
Price
$582
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0019178
Product name
QUINALDOPEPTIN
Purity
95.00%
Packaging
0.5MG
Price
$646
Updated
2021/12/16
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quinaldopeptin Chemical Properties,Usage,Production

Description

Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).

Uses

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumour, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.

Uses

Quinaldopeptin is a bis-intercalating cyclic peptide antibiotic.

quinaldopeptin Preparation Products And Raw materials

Raw materials

Preparation Products

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quinaldopeptin Suppliers

Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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info@efebio.com
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China
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Lynnchem
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86-(0)29-85992781 17792393971
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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Meng Cheng Technology (Shanghai) Co., LTD
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Energy Chemical
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Boao Pike
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