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sphondin

Product Name
sphondin
CAS No.
483-66-9
Chemical Name
sphondin
Synonyms
Sfondin;sphondin;6-Methoxyangelicin;sphondin, 10 mM in DMSO;6-Methoxy-2H-furo[2,3-h]chromen-2-one;6-Methoxy-2H-furo[2,3-h]-1-benzopyran-2-one;6-Methoxy-2H-furo[2,3-h][1]benzopyran-2-one;2H-Furo(2,3-h)-1-benzopyran-2-one, 6-Methoxy-
CBNumber
CB51322315
Molecular Formula
C12H8O4
Formula Weight
216.19
MOL File
483-66-9.mol
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sphondin Property

Melting point:
189-191 °C
Boiling point:
413.0±45.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
color 
Off-white to light yellow
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Safety

Hazardous Substances Data
483-66-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0022643
Product name
Sphondin
Packaging
1mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0022643
Product name
Sphondin
Packaging
5mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
W1276
Product name
Sphondin
Packaging
25mg
Price
$416
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001957
Product name
SPHONDIN
Purity
95.00%
Packaging
5MG
Price
$498.26
Updated
2021/12/16
ChemScene
Product number
CS-0022643
Product name
Sphondin
Packaging
10mg
Price
$595
Updated
2021/12/16
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sphondin Chemical Properties,Usage,Production

Chemical Properties

Off-white needle-like crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Oxtail Duhuo.

Uses

Sphondin has an Analgesic, anti-inflammatory, anti-allergic, smooth muscle spasmolytic effect.

Definition

ChEBI: Sphondin is a furanocoumarin.

Biological Activity

Sphondin, isolated from Heracleum laciniatum, has inhibitory effects on IL-1β-induced increases in COX-2 protein and PGE2 release levels in A549 cells.

in vitro

Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE 2 release.

target

COX-2

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sphondin Preparation Products And Raw materials

Raw materials

Preparation Products

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sphondin Suppliers

China 108 United Kingdom 1 United States 7 Global 116
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4790
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5645
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
5000
Advantage
60
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Fax
086-28-85377358
Email
2355253622@qq.com;
Country
China
ProdList
1089
Advantage
58
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
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View Lastest Price from sphondin manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
sphondin 483-66-9
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06

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  • sphondin
  • 6-Methoxy-2H-furo[2,3-h][1]benzopyran-2-one
  • 6-Methoxy-2H-furo[2,3-h]-1-benzopyran-2-one
  • 2H-Furo(2,3-h)-1-benzopyran-2-one, 6-Methoxy-
  • Sfondin
  • 6-Methoxy-2H-furo[2,3-h]chromen-2-one
  • 6-Methoxyangelicin
  • sphondin, 10 mM in DMSO
  • 483-66-9