Scabertopin

Product Name: Scabertopin
CAS No.: 185213-52-9
Chemical Name: Scabertopin
Synonyms: Scabertopin;Scabertopin, 10 mM in DMSO;Gpr52 antagonist E7 (Scabertopin);2-Butenoic acid, 2-methyl-, (3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester, (2Z)-
CBNumber: CB52566732
Molecular Formula: C20H22O6
Formula Weight: 358.39
MOL File: 185213-52-9.mol

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Scabertopin Property

Boiling point:: 592.7±50.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
form: Solid
color: White to light yellow
InChI: InChI=1S/C20H22O6/c1-5-11(3)18(21)25-16-9-13-8-14(24-20(13)23)6-10(2)7-15-17(16)12(4)19(22)26-15/h5,7-8,14-17H,4,6,9H2,1-3H3/b10-7+,11-5-/t14-,15+,16-,17-/m0/s1
InChIKey: FTPHYXGWMIZVMP-RZYABJHASA-N
SMILES: C(O[C@H]1CC2=C[C@]([H])(CC(C)=C[C@@]3([H])OC(=O)C(=C)[C@@]31[H])OC2=O)(=O)/C(/C)=C\C |t:10|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0016650
Product name: Scabertopin
Purity: >99.0%
Packaging: 5mg
Price: $650
Updated: 2021/12/16

Arctom

Product number: CFN97798
Product name: Scabertopin
Purity: ≥98%
Packaging: 5mg
Price: $413
Updated: 2021/12/16

Crysdot

Product number: CD32002161
Product name: Scabertopin
Purity: 95+%
Packaging: 5mg
Price: $860
Updated: 2021/12/16

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Scabertopin Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Elephantopus scaber.

Uses

Scabertopin is a sesquiterpene lactone. Scabertopin has been found to be prominent anticancer constituents[1][2].

Health effects

Didancao species lactone has anti-tumor effect: Didancao has inhibitory effect on the proliferation of various tumor cells.

Biological Activity

Scabertopin, isolated from Elephantopus scaber, is a sesquiterpene lactone. It is an important anticancer ingredient.

References

[1] Liang QL, et al. [Structure modification on sesquiterpene lactones from Elephantopus scaber]. Yao Xue Xue Bao. 2007 Nov;42(11):1159-61. PMID:18300472
[2] Hiradeve SM, et al. A review on pharmacology and toxicology of Elephantopus scaber Linn. Nat Prod Res. 2014;28(11):819-30. DOI:10.1080/14786419.2014.883394

Scabertopin Preparation Products And Raw materials

Raw materials

Preparation Products

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Scabertopin Suppliers

China 95 United States 4 Global 99

Chengdu Herbpurify Co.Ltd.

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Scabertopin

Gpr52 antagonist E7 (Scabertopin)

2-Butenoic acid, 2-methyl-, (3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester, (2Z)-

Scabertopin, 10 mM in DMSO

185213-52-9