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Piclamilast

Product Name
Piclamilast
CAS No.
144035-83-6
Chemical Name
Piclamilast
Synonyms
RP 73401;RPR 73401;piclamilas;Piclamilast;N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide;3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide;Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-;inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP
CBNumber
CB51328847
Molecular Formula
C18H18Cl2N2O3
Formula Weight
381.25
MOL File
144035-83-6.mol
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Piclamilast Property

Boiling point:
447.8±45.0 °C(Predicted)
Density 
1.370
storage temp. 
2-8°C
solubility 
DMSO: soluble20mg/mL, clear
pka
10.10±0.70(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0585
Product name
Piclamilast
Purity
≥98% (HPLC)
Packaging
5mg
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0585
Product name
Piclamilast
Purity
≥98% (HPLC)
Packaging
25mg
Price
$496
Updated
2024/03/01
Cayman Chemical
Product number
29170
Product name
Piclamilast
Packaging
1mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
29170
Product name
Piclamilast
Packaging
5mg
Price
$127
Updated
2024/03/01
Cayman Chemical
Product number
29170
Product name
Piclamilast
Packaging
10mg
Price
$233
Updated
2024/03/01
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Piclamilast Chemical Properties,Usage,Production

Uses

Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor. Piclamilast may offer therapeutic strategies in respiratory diseases, including asthma and chronic obstructive pulmonary disease. Piclamilast may also provide a treatment option for pre-term infants with bronchopulmonary dysplasia (BPD).

Definition

ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.

storage

Store at RT

Piclamilast Preparation Products And Raw materials

Raw materials

Preparation Products

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Piclamilast Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
sales@zhiwe.net
Country
China
ProdList
604
Advantage
61
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1830
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Shanghai Boyners Pharm-Tech Co., Ltd.
Tel
021-54581719 13817873692
Fax
021-31329586
Email
mkt@boynerspharm.com
Country
China
ProdList
1722
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56902
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58

144035-83-6, PiclamilastRelated Search:


  • Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-
  • RP 73401
  • RPR 73401
  • 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide
  • 3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide
  • N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide
  • Piclamilast
  • 3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
  • piclamilas
  • inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP
  • 144035-83-6
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals