Piclamilast
- Product Name
- Piclamilast
- CAS No.
- 144035-83-6
- Chemical Name
- Piclamilast
- Synonyms
- RP 73401;RPR 73401;piclamilas;Piclamilast;N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide;3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide;Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-;inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP
- CBNumber
- CB51328847
- Molecular Formula
- C18H18Cl2N2O3
- Formula Weight
- 381.25
- MOL File
- 144035-83-6.mol
Piclamilast Property
- Boiling point:
- 447.8±45.0 °C(Predicted)
- Density
- 1.370
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- pka
- 10.10±0.70(Predicted)
- form
- powder
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0585
- Product name
- Piclamilast
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $128
- Updated
- 2024/03/01
- Product number
- SML0585
- Product name
- Piclamilast
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $496
- Updated
- 2024/03/01
- Product number
- 29170
- Product name
- Piclamilast
- Packaging
- 1mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 29170
- Product name
- Piclamilast
- Packaging
- 5mg
- Price
- $127
- Updated
- 2024/03/01
- Product number
- 29170
- Product name
- Piclamilast
- Packaging
- 10mg
- Price
- $233
- Updated
- 2024/03/01
Piclamilast Chemical Properties,Usage,Production
Uses
Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor. Piclamilast may offer therapeutic strategies in respiratory diseases, including asthma and chronic obstructive pulmonary disease. Piclamilast may also provide a treatment option for pre-term infants with bronchopulmonary dysplasia (BPD).
Definition
ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.
storage
Store at RT