Piclamilast

Product Name: Piclamilast
CAS No.: 144035-83-6
Chemical Name: Piclamilast
Synonyms: RP 73401;RPR 73401;piclamilas;Piclamilast;N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide;3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide;3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide;Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-;inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP
CBNumber: CB51328847
Molecular Formula: C18H18Cl2N2O3
Formula Weight: 381.25
MOL File: 144035-83-6.mol

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Piclamilast Property

Boiling point:: 447.8±45.0 °C(Predicted)
Density: 1.370
storage temp.: 2-8°C
solubility: DMSO: soluble20mg/mL, clear
pka: 10.10±0.70(Predicted)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0585
Product name: Piclamilast
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $128
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0585
Product name: Piclamilast
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $496
Updated: 2024/03/01

Cayman Chemical

Product number: 29170
Product name: Piclamilast
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 29170
Product name: Piclamilast
Packaging: 5mg
Price: $127
Updated: 2024/03/01

Cayman Chemical

Product number: 29170
Product name: Piclamilast
Packaging: 10mg
Price: $233
Updated: 2024/03/01

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Piclamilast Chemical Properties,Usage,Production

Uses

Piclamilast is a potent and selective phosphodiesterase-4 (PDE4) inhibitor. Piclamilast may offer therapeutic strategies in respiratory diseases, including asthma and chronic obstructive pulmonary disease. Piclamilast may also provide a treatment option for pre-term infants with bronchopulmonary dysplasia (BPD).

Definition

ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 3-(cyclopentyloxy)-4-methoxybenzoic acid with the primary amino group of 3,5-dichloropyridin-4-amine.

storage

Store at RT

Piclamilast Preparation Products And Raw materials

Raw materials

Preparation Products

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Piclamilast Suppliers

Canada 1 China 22 India 1 United Kingdom 1 United States 10 USA 1 Global 36

J & K SCIENTIFIC LTD.

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144035-83-6, PiclamilastRelated Search:

3-ISOPROPOXY-4-METHOXY-BENZALDEHYDE 4-Benzylaminopyridine 3-ETHOXY-4-METHOXY-BENZYLAMINE 3-BUTOXY-4-METHOXYBENZAMIDE N1-(4-PYRIDYL)BENZAMIDE 3-CYCLOPENTYLOXY-4-METHOXYBENZALDEHYDE CHEMBRDG-BB 9071037 (3,5-DICHLORO-PYRIDIN-4-YL)METHYLAMINE 3-ISOPROPOXY-BENZALDEHYDE Piclamilast BENZYL-PYRIDIN-4-YL-AMINE DIHYDROCHLORIDE 3-(SEC-BUTOXY)PHENYL]METHANAMINE 3-(CYCLOPENTYLOXY)-4-METHOXYBENZAMIDE 3-(CYCLOPENTYLOXY)BENZALDEHYDE CHEMBRDG-BB 5563263 1-(3-ISOPROPOXYPHENYL)METHANAMINE

Benzamide,3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-

RP 73401

RPR 73401

3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridyl)-4-methoxybenzamide

3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxybenzamide

N-(3,5-Dichloropyrid-4-yl)-3-cyclopentyloxy-4-methoxybenzamide

Piclamilast

3-(Cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide

piclamilas

inhibit,Phosphodiesterase (PDE),RPR73401,AML,phosphodiesterase,PDE,RAR,RP-73401,Inhibitor,Piclamilast,RP73401,RPR-73401,ATRA,cAMP

144035-83-6

Aromatics

Heterocycles

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals