irisolidone

ChemicalBook > CAS DataBase List > irisolidone

Product Name: irisolidone
CAS No.: 2345-17-7
Chemical Name: irisolidone
Synonyms: irisoidone;irisolidone;4'-Methoxytectorigenin;4'-O-Methyltectorigenin;5,7-Dihydroxy-6,4'-dimethoxyisoflavon;5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one;5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-;Chloride Channel,Cl? Channels,Inhibitor,hepatoprotective,inhibit,VRAC,Irisolidone
CBNumber: CB51330783
Molecular Formula: C17H14O6
Formula Weight: 314.29
MOL File: 2345-17-7.mol

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irisolidone Property

Melting point:: 190-191 °C
Boiling point:: 565.5±50.0 °C(Predicted)
Density: 1.402±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Solid
pka: 6.48±0.20(Predicted)
color: Off-White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Arctom

Product number: SY232783
Product name: 5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one
Purity: ≥95%
Packaging: 10mg
Price: $619.09
Updated: 2021/12/16

Arctom

Product number: AS671770
Product name: Irisolidone
Purity: 98%
Packaging: 100mg
Price: $787
Updated: 2021/12/16

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irisolidone Chemical Properties,Usage,Production

Description

Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.

Chemical Properties

Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.

Uses

Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.

Definition

ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.

Biological Activity

Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.

in vitro

Irisolidone shows the high efficacy for Volume-regulated anion channels (VRAC) blockade with an IC ₅₀ of 9.8 μM in HEK293 cells.
It can inhibit endothelial cell proliferation.

irisolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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2345-17-7, irisolidoneRelated Search:

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irisolidone

5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one

irisoidone

4'-Methoxytectorigenin

4'-O-Methyltectorigenin

5,7-Dihydroxy-6,4'-dimethoxyisoflavon

4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-

5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one

Chloride Channel,Cl? Channels,Inhibitor,hepatoprotective,inhibit,VRAC,Irisolidone

2345-17-7