xanthatin
- Product Name
- xanthatin
- CAS No.
- 26791-73-1
- Chemical Name
- xanthatin
- Synonyms
- ( - ) - xanthatin;Xanthatin, 10 mM in DMSO;(3aR)-3-Methylene-7β-methyl-6-(3-oxo-1-butenyl)-3,3aα,4,7,8,8aβ-hexahydro-2H-cyclohepta[b]furan-2-one;(3aR)-3,3aα,4,7,8,8aβ-Hexahydro-7β-methyl-3-methylene-6-(3-oxo-1-butenyl)-2H-cyclohepta[b]furan-2-one;(3aR,7S,8aS)-7-methyl-3-methylidene-6-[(E)-3-oxobut-1-enyl]-4,7,8,8a-tetrahydro-3aH-cyclohepta[b]furan-2-one;2H-Cyclohepta[b]furan-2-one,3,3a,4,7,8,8a-hexahydro-7-Methyl-3-Methylene-6-(3-oxo-1-buten-1-yl)-,(3aR,7S,8aS)-;(3aR,7S,8aS)-7-Methyl-3-methylene-6-((E)-3-oxobut-1-en-1-yl)-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one;(3aR,7S,8aS)-7-methyl-3-methylidene-6-[(1E)-3-oxobut-1-en-1-yl]-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one;2H-Cyclohepta[b]furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-[(1E)-3-oxo-1-buten-1-yl]-, (3aR,7S,8aS)-;cancer,Xanthatin,5-lipoxygenase,inhibit,Bacterial,Lipoxygenase,antiinflammatory,LOX,T. b. brucei,Apoptosis,VEGFR,breast,Inhibitor,Vascular endothelial growth factor receptor,parasite
- CBNumber
- CB51390675
- Molecular Formula
- C15H18O3
- Formula Weight
- 246.3
- MOL File
- 26791-73-1.mol
xanthatin Property
- Melting point:
- 114.5-115°
- alpha
- D30 -20° (ethanol)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- form
- powder
- Boiling point:
- 444.3±45.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0023046
- Product name
- Xanthatin
- Purity
- 99.79%
- Packaging
- 5mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- N2067
- Product name
- Xanthatin
- Packaging
- 5mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- CS-0023046
- Product name
- Xanthatin
- Purity
- 99.79%
- Packaging
- 10mg
- Price
- $215
- Updated
- 2021/12/16
- Product number
- CS-0023046
- Product name
- Xanthatin
- Purity
- 99.79%
- Packaging
- 50mg
- Price
- $775
- Updated
- 2021/12/16
- Product number
- CS-0023046
- Product name
- Xanthatin
- Purity
- 99.79%
- Packaging
- 100mg
- Price
- $1335
- Updated
- 2021/12/16
xanthatin Chemical Properties,Usage,Production
Definition
ChEBI: Xanthatin is a sesquiterpene lactone.
Biological Activity
Potent anticancer agent th at induces cell cycle arrest at the G2/M phase.
Xanthatin, a sesquiterpene lactone isolated from Xanthium plants (Asteraceae), is a potent anticancer agent th at induces cell cycle arrest at the G2/M phase in hepatocellular carcinoma and colon cancer cells. Xanthatin induces apoptosis in numerous cancer cell lines including colon, breast, lung, cervix, and skin cancers, while apparently spearing human normal LO2 hepatocytes. It appears to activate endoplasmic reticulum stress through activation of the PERK/eIF-2α/ATF4 axis in hepatocellular carcinoma cells. Also, xanthatin exhibit potent phytotoxic activity, which suppressed root growth of receiver plants.
Purification Methods
Crystallise xanthatin from MeOH, aqueous MeOH, EtOH or aqueous EtOH. UV: 213 and 275nm (max 7300). The 2,4-dinitrophenylhydrazone has m 240o(dec) (twice recrystallised from CHCl3/MeOH). [Geissman et al. J Am Chem Soc 76 685 1954, Deuel & Geissman J Am Chem Soc 79 3778 1957, Beilstein 17 III/IV 6221, 17/1 V 305.]
xanthatin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from xanthatin manufacturers
- Product
- Xanthatin 26791-73-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-13
- Product
- xanthatin 26791-73-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- KG/T
- Release date
- 2019-12-18