irisolidone

Product Name: irisolidone
CAS No.: 2345-17-7
Chemical Name: irisolidone
Synonyms: irisoidone;irisolidone;4'-Methoxytectorigenin;4'-O-Methyltectorigenin;Irisolidone, 10 mM in DMSO;5,7-Dihydroxy-6,4'-dimethoxyisoflavon;5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one;5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-;Chloride Channel,Cl? Channels,Inhibitor,hepatoprotective,inhibit,VRAC,Irisolidone
CBNumber: CB51330783
Molecular Formula: C17H14O6
Formula Weight: 314.29
MOL File: 2345-17-7.mol

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irisolidone Property

Melting point:: 190-191 °C
Boiling point:: 565.5±50.0 °C(Predicted)
Density: 1.402±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 6.48±0.20(Predicted)
form: Solid
color: Off-White to Pale Yellow
InChI: InChI=1S/C17H14O6/c1-21-10-5-3-9(4-6-10)11-8-23-13-7-12(18)17(22-2)16(20)14(13)15(11)19/h3-8,18,20H,1-2H3
InChIKey: VOOFPOMXNLNEOF-UHFFFAOYSA-N
SMILES: C1OC2=CC(O)=C(OC)C(O)=C2C(=O)C=1C1=CC=C(OC)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Arctom

Product number: SY232783
Product name: 5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one
Purity: ≥95%
Packaging: 10mg
Price: $619.09
Updated: 2021/12/16

Arctom

Product number: AS671770
Product name: Irisolidone
Purity: 98%
Packaging: 100mg
Price: $787
Updated: 2021/12/16

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irisolidone Chemical Properties,Usage,Production

Description

Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.

Chemical Properties

Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.

Uses

Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.

Definition

ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.

Biological Activity

Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.

in vitro

Irisolidone shows the high efficacy for Volume-regulated anion channels (VRAC) blockade with an IC ₅₀ of 9.8 μM in HEK293 cells.
It can inhibit endothelial cell proliferation.

irisolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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irisolidone Suppliers

China 87 United States 4 Global 91

Huzhou ZhanShu Biotechnology Co.,Ltd

Tel: 0572-8889530 18167260939
Email: zsubio@163.com
Country: China
ProdList: 392
Advantage: 58

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Winherb Medical Technology Co., Ltd.

Tel: 021-38218169 13341702378
Fax: QQ：190129269
Email: winherb@126.com
Country: China
ProdList: 1245
Advantage: 58

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

Shanghai Zhanshu Chemical Technology Co., Ltd

Tel: +86-21-58589556
Fax: +86-21-58589557
Country: China
ProdList: 413
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

2345-17-7, irisolidoneRelated Search:

hydroxygenkwanin kakkalide Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) MEDICAGOL Quercetin-7-O-β-D-glucopyranoside GARDENIN B Naringenin PONCIRIN 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one MOSLOFLAVONE 4',5-DIHYDROXY-7-METHOXYFLAVONE Isoflavone Puerarin Puerarin Isoflavones 5,7-dihydroxy-6-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)ox an-2-yl]-2-[4-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan -2-yl]oxyphenyl]chromen-4-one xanthatin (3aS)-3aβ,4,5,7,8,9,9aβ,9bα-Octahydro-9β-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one 7-Xylosyl-10-deacetyltaxol

irisolidone

5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one

irisoidone

4'-Methoxytectorigenin

4'-O-Methyltectorigenin

5,7-Dihydroxy-6,4'-dimethoxyisoflavon

4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-

5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one

Chloride Channel,Cl? Channels,Inhibitor,hepatoprotective,inhibit,VRAC,Irisolidone

Irisolidone, 10 mM in DMSO

2345-17-7