Carboxyatractyloside

Product Name: Carboxyatractyloside
CAS No.: 77228-71-8
Chemical Name: Carboxyatractyloside
Synonyms: Carboxyatractyloside, 10 mM in DMSO;Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Carboxyatractyloside potassium salt - Bio-X ?;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber: CB62677293
Molecular Formula: C31H46O18S2
Formula Weight: 770.81
MOL File: 77228-71-8.mol

More

Less

Carboxyatractyloside Property

Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: H2O: ≥10mg/mL
pka: -3?+-.0.18(Predicted)
form: solid
color: white
biological source: Xanthium sibiricum
optical activity: [α]/D -34 to -48°, c =0.5 in water
Water Solubility: H2O: ≥10mg/mL

More

Less

Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 36/37-45
RIDADR: UN 2811 6.1 / PGI
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C4992
Product name: Carboxyatractyloside potassium salt
Purity: ≥98% (HPLC), from
Packaging: 2mg
Price: $199
Updated: 2023/01/07

ChemScene

Product number: CS-0017047
Product name: Carboxyatractyloside
Packaging: 5mg
Price: $250
Updated: 2021/12/16

AvaChem

Product number: 3202A
Product name: Carboxyatractyloside
Packaging: 10mg
Price: $290
Updated: 2021/12/16

Arctom

Product number: AS713545
Product name: Carboxyatractyloside
Purity: ≥98%
Packaging: 100mg
Price: $342
Updated: 2021/12/16

Crysdot

Product number: CD11059260
Product name: Carboxyatractylosidetripotassiumsalt
Purity: 97%
Packaging: 10mg
Price: $380
Updated: 2021/12/16

More

Less

Carboxyatractyloside Chemical Properties,Usage,Production

Chemical Properties

White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Atractylodes lancea.

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca²⁺-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Carboxyatractyloside Suppliers

China 143 India 1 United Kingdom 1 United States 10 Global 155

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Cheng Du Pufeide Biotechnology Co., Ltd.

Tel: 028-82610909 13388174823
Fax: 8171-1798
Email: scglp@glp-china.com
Country: China
ProdList: 1064
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

More

Less

View Lastest Price from Carboxyatractyloside manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Carboxyatractyloside Potassium Salt 77228-71-8
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-03

Career Henan Chemical Co

Product: Carboxyatractyloside tripotassium salt 77228-71-8
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

77228-71-8, CarboxyatractylosideRelated Search:

3-Dimethylamino-1-propanol Acetoin Cupric acetate monohydrate Madecassoside ATRACTYLOSIDE POTASSIUM SALT ALLEOSIDE A Terrestrosin D xanthatin Xanthiside roburic acid Poricoic acid A(F) Pachymic acid 1,3,5-Tricaffeoylquinic acid Terrestrosin K Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate

(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid

Carboxyatractyloside tripotassium salt

Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-

Carboxyatractylosidetripotassiumsal

Carboxyatractyloside, 10 mM in DMSO

Carboxyatractyloside potassium salt - Bio-X ?

77228-71-8

C31H46O18S2

C31H43O18S2K3

C31H43K3O18S2

reagent

standard substance

chemical reagent

herbal extract

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).