Carboxyatractyloside

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Carboxyatractyloside

Product Name: Carboxyatractyloside
CAS No.: 77228-71-8
Chemical Name: Carboxyatractyloside
Synonyms: Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber: CB62677293
Molecular Formula: C31H46O18S2
Formula Weight: 770.81
MOL File: 77228-71-8.mol

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Carboxyatractyloside Property

Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: H2O: ≥10mg/mL
pka: -3?+-.0.18(Predicted)
form: solid
color: white

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 36/37-45
RIDADR: UN 2811 6.1 / PGI
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C4992
Product name: Carboxyatractyloside potassium salt
Purity: ≥98% (HPLC), from
Packaging: 2mg
Price: $199
Updated: 2023/01/07

ChemScene

Product number: CS-0017047
Product name: Carboxyatractyloside
Packaging: 5mg
Price: $250
Updated: 2021/12/16

AvaChem

Product number: 3202A
Product name: Carboxyatractyloside
Packaging: 10mg
Price: $290
Updated: 2021/12/16

Arctom

Product number: AS713545
Product name: Carboxyatractyloside
Purity: ≥98%
Packaging: 100mg
Price: $342
Updated: 2021/12/16

Crysdot

Product number: CD11059260
Product name: Carboxyatractylosidetripotassiumsalt
Purity: 97%
Packaging: 10mg
Price: $380
Updated: 2021/12/16

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Carboxyatractyloside Chemical Properties,Usage,Production

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca²⁺-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Carboxyatractyloside manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Carboxyatractyloside Potassium Salt 77228-71-8
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-03

Career Henan Chemical Co

Product: Carboxyatractyloside tripotassium salt 77228-71-8
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

77228-71-8, CarboxyatractylosideRelated Search:

3-Dimethylamino-1-propanol Acetoin Cupric acetate monohydrate Madecassoside ATRACTYLOSIDE POTASSIUM SALT ALLEOSIDE A Terrestrosin D xanthatin Xanthiside roburic acid Poricoic acid A(F) Pachymic acid 1,3,5-Tricaffeoylquinic acid Terrestrosin K Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate

(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid

Carboxyatractyloside tripotassium salt

Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-

Carboxyatractylosidetripotassiumsal

Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-

77228-71-8

C31H46O18S2

reagent

standard substance

chemical reagent

herbal extract

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).