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roemerine

Product Name
roemerine
CAS No.
548-08-3
Chemical Name
roemerine
Synonyms
Remerin;roemerine;(-)-Remerine;(-)-Roemarine;(-)-Aporheine;(–)-roemerine;(-)-Roemerine;Remerine【alkaloid】;Roemerine【alkaloid】;(-)-N-Methylanonaine
CBNumber
CB51332136
Molecular Formula
C18H17NO2
Formula Weight
279.33
MOL File
548-08-3.mol
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roemerine Property

Melting point:
102-103℃
Boiling point:
424.0±34.0 °C(Predicted)
Density 
1.269±0.06 g/cm3 (20 ºC 760 Torr)
solubility 
Chloroform: soluble
form 
A solid
pka
7.87±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
R639600
Product name
Roemerine
Packaging
10mg
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0002146
Product name
ROEMERINE
Purity
95.00%
Packaging
5MG
Price
$499.97
Updated
2021/12/16
AvaChem
Product number
4430
Product name
Roemerine
Packaging
20mg
Price
$690
Updated
2021/12/16
AvaChem
Product number
4430
Product name
Roemerine
Packaging
1mg
Price
$119
Updated
2021/12/16
AvaChem
Product number
4430
Product name
Roemerine
Packaging
5mg
Price
$290
Updated
2021/12/16
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roemerine Chemical Properties,Usage,Production

Uses

Roemerine is an (-)-aporphine type of alkaloid which has been shown to possess significant antibacterial activity against Escheria Coli.

Definition

ChEBI: Remerin is an isoquinoline alkaloid.

in vivo

Roemerine (30 mg/kg, i.p., once every three days for 30 days) significantly inhibited tumor growth in the prostate cancer BALB/C nude mouse model (established by subcutaneous implantation of RM-1 cells)[2]. Roemerine (20 mg/kg, i.p., once daily for 2 days) increases survival and reduced bacterial loads in multiple organs in the MRSA XJ75302-induced sepsis BALB/C mouse model[5].

Animal Model:Prostate cancer BALB/C nude mouse model (established by subcutaneous implantation of RM-1 cells)[3]
Dosage:30 mg/kg
Administration:Intraperitoneal injection (i.p.), once every three days for 30 days
Result:Significantly reduced tumor volume and weight in the experimental group (P < 0.05), with an inhibition rate of 41.2%.
Animal Model:MRSA XJ75302-induced sepsis BALB/C mouse model[5]
Dosage:20 mg/kg
Administration:Intraperitoneal injection (i.p.), once daily, for 2 days
Result:Increased the 7-day survival rate of mice to 58.3% (p < 0.05) and reduced bacterial loads in the liver (4.71 to 4.38 log CFU/mL), kidney (4.37 to 3.79 log CFU/mL), heart (5.44 to 3.76 log CFU/mL), and blood (6.52 to 4.55 log CFU/mL). Note: CFU/mL represents the number of bacteria per milliliter of culture medium or tissue sample that can form colonies (CFU, Colony-Forming Units).

roemerine Preparation Products And Raw materials

Raw materials

Preparation Products

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roemerine Suppliers

China 65 United States 8 USA 1 Global 74
Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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051085625359
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sales@reading-chemicals.com
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China
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Wuhan ChemFaces Biochemical Co., Ltd.
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18607101326 15172504745
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+86-27-84254680
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aileen@chemfaces.com
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China
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EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
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8447
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60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
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China
ProdList
71826
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Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
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China
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29760
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
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010-60605840
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psaitong@jm-bio.com
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China
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12306
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Shanghai Uteam Biotechnology Co., Ltd.
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021-36031160 13311776681
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3338195766@QQ.com
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China
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Shanghai Biological Technology Development Co., Ltd.
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021-69955236-807 13918189704
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021-65211385
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chinaruji@chinaruji.com
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China
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5095
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Chengdu Push Bio-Technology Co., Ltd.
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028-028-85370565-229-229 18080489829
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18080489829@163.com
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China
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8250
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60
Shanghai Standard Technology Co.,Ltd.
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021-021-57127007-6622-6622 17621252073
Fax
+86 (21) 5132-0077
Email
luzh@nature-standard.com
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China
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3021
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548-08-3, roemerineRelated Search:

2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one L-Hyoscyamine Xanthiazone menisdaurin Lotusine Liensinine diperchlorate VERATRIDINE (R)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium Isoliensinine daurisoline Liensinine stephanine crebanine 1,2-METHYLENEDIOXY-11-HYDROXYAPORPHIN roemerine REMERINEHYDROCHLORIDE STEPORPHINE USHINSUNINE

  • roemerine
  • (-)-N-Methylanonaine
  • (-)-Roemerine【alkaloid】
  • (6aR)-6-Methyl-1,2-(methylenedioxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
  • [7aR,(-)]-6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
  • Remerine【alkaloid】
  • Roemerine【alkaloid】
  • (-)-Remerine
  • (-)-Roemarine
  • 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-7-methyl-, (7aR)-
  • (-)-Aporheine
  • (–)-roemerine
  • Remerin
  • (-)-Roemerine
  • 548-08-3