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paraherquamide

Product Name
paraherquamide
CAS No.
77392-58-6
Chemical Name
paraherquamide
Synonyms
VM 29919;paraherquamide;(-)-Paraherquamide A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CBNumber
CB51336725
Molecular Formula
C28H35N3O5
Formula Weight
493.59
MOL File
77392-58-6.mol
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paraherquamide Property

Melting point:
244-247° (dec)
alpha 
D22 -28° (c = 0.43 in methanol)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
White to off-white powder.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26685
Product name
Paraherquamide A
Packaging
1mg
Price
$347
Updated
2024/03/01
Cayman Chemical
Product number
26685
Product name
Paraherquamide A
Packaging
5mg
Price
$1210
Updated
2024/03/01
TRC
Product number
P193278
Product name
ParaherquamideA
Packaging
0.5mg
Price
$560
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004348
Product name
PARAHERQUAMIDE A
Purity
95.00%
Packaging
1MG
Price
$538.65
Updated
2021/12/16
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paraherquamide Chemical Properties,Usage,Production

Description

Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).

Uses

Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent, non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.

Uses

Paraherquamide A is a selective, competitive, cholinergic antagonist.

paraherquamide Preparation Products And Raw materials

Raw materials

Preparation Products

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paraherquamide Suppliers

China 12 India 1 United Kingdom 1 United States 4 Global 18
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56902
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58

77392-58-6, paraherquamideRelated Search:

3-Isobutyl-2-oxindole 2-Amino-2,3-dimethylbutyramide trans-2,5-Dimethylpiperazine 6-Methoxy-2-oxindole (S)-3-Aminopiperidine 2,5-Diazabicyclo[2.2.2]octane 7-METHOXYOXINDOLE (1,4-DIMETHYL-2-PIPERAZINYL)METHANOL (S)-2-HYDROXYMETHYL-PIPERAZINE N-[1-(aminomethyl)cyclopentyl]-N,N-dimethylamine (1S,4S)-2,5-DIAZABICYCLO(2.2.2)OCTANE 7-METHOXY-2,3-DIHYDRO-1H-INDOLE [1-(3,4-DIMETHOXYPHENYL)CYCLOPENTYL]METHANAMINE R-2-ISOPROPYL-PIPERAZINE Piperazine, 1,2,2-trimethyl- (9CI) 1,2-BIS(DIMETHYLAMINO)-2-METHYLPROPANE 2-PIPERIDIN-3-YLPROPAN-2-OL N'-CYCLOPENTYL-N,N-DIMETHYL-ETHANE-1,2-DIAMINE

  • paraherquamide
  • VM 29919
  • Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
  • (-)-Paraherquamide A
  • 77392-58-6