4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

Product Name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
CAS No.: 757251-39-1
Chemical Name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
Synonyms: RG-M2;Regofenib impurity 4;Regorafenib USP RC A;Regorafenib Impurity 35;Regorafenib Intermediate;Regorafenib EP Impurity A;4-(4-amino-3-fluorophenoxy);AFP-Picolin Methylamide Impurity;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE;4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
CBNumber: CB51486673
Molecular Formula: C13H12FN3O2
Formula Weight: 261.25
MOL File: 757251-39-1.mol

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Property

Melting point:: 143 °C
Boiling point:: 459.8±45.0 °C(Predicted)
Density: 1.305
vapor pressure: 0Pa at 20℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
form: Solid
pka: 13.92±0.46(Predicted)
color: Orange to Dark Red to Brown
Water Solubility: 190mg/L at 20℃
LogP: 1.3 at 25℃

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Safety

HS Code: 2933.39.9200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002093
Product name: Regorafenib impurity A
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002093
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: A2979
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $37
Updated: 2024/03/01

TCI Chemical

Product number: A2979
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $110
Updated: 2024/03/01

TRC

Product number: A609725
Product name: 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
Packaging: 1g
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0352095
Product name: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $502.98
Updated: 2021/12/16

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Chemical Properties,Usage,Production

Chemical Properties

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport.

Uses

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.

Definition

ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether.

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE Suppliers

Americas 1 China 222 Europe 1 India 12 Japan 1 Switzerland 1 United Kingdom 1 United States 13 Global 252

Yangzhou QinYuan Pharmaceutical Co., Ltd.

Tel: 0514-80939770 13773367191
Fax: 0514-82664689
Email: yzqyyykj@163.com
Country: China
ProdList: 240
Advantage: 55

Wuhan Yihe Technology Co., Ltd

Tel: 18427358861 18427358864
Email: yihekeji@chembuying.com
Country: China
ProdList: 775
Advantage: 58

Hubei Kanglide Bio-pharmaceutical Co., Ltd

Tel: 19307248857
Email: 1901338096@qq.com
Country: China
ProdList: 506
Advantage: 58

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5047
Advantage: 50

Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.

Tel: 022-60116533 13207668525
Fax: 022-60979672
Email: saleskc@scipharmacn.com
Country: China
ProdList: 683
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8878
Advantage: 55

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View Lastest Price from 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE manufacturers

LY Global chemicals co.,ltd .

Product: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE 757251-39-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.0%min
Supply Ability: 100kg
Release date: 2023-03-11

Shanghai Rlavie Technology Co ltd

Product: 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide 757251-39-1
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 50kgs/month
Release date: 2022-09-11

Career Henan Chemical Co

Product: 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE 757251-39-1
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-13

757251-39-1, 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDERelated Search:

1,3-Benzenediol, 5-fluoro-4-nitro- 4-(4-Fluorophenyl)-1-Methyl- Paroxetine Selexipag Impurity 6 (4-BENZYLOXYCARBONYLAMINOPHENYL)BORONIC ACID, PINACOL ESTER PAROXETINE RELATED COMPOUND C (15 MG) ((+)-TRANS-PAROXETINE HYDROCHLORIDE) S-Silodosin 6,6'-bis(2-methyl-2H-tetrazol-5-yl)-3,3'-bipyridine 2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid Cabozantinib Impurity E 4-Amino-3-fluorophenol 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrate 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine Regorafenib Regorafenib iMpurity Benzene, 1-chloro-3-isocyanato-5-(trifluoromethyl)- 2-Pyridinecarboxylic acid, 4,5,6-trichloro-, methyl ester 1,3-Benzenediol, 4-amino-5-fluoro-

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE

2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-

4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamine

4-(4-amino-3-fluorophenoxy)

4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamid

Regorafenib Impurity 35

4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide EINECS

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE

Regorafenib Intermediate

Regofenib impurity 4

AFP-Picolin Methylamide Impurity

Regorafenib USP RC A

Regorafenib EP Impurity A

AFP-Picolin Methylamide ImpurityQ: What is AFP-Picolin Methylamide Impurity Q: What is the CAS Number of AFP-Picolin Methylamide Impurity Q: What is the storage condition of AFP-Picolin Methylamide Impurity Q: What are the applications of AFP-Picolin Methylamide Impurity

RG-M2

Regorafenib EP Impurity A (Regorafenib USP Related Compound A)

4- (4-Amino-3-fluorophenoxy) - N-methyl-2-pyridylformamide

757251-39-1

797251-39-1

Regorafenib