ChemicalBook > CAS DataBase List > 4-ISOBUTOXY-BENZALDEHYDE

4-ISOBUTOXY-BENZALDEHYDE

Product Name
4-ISOBUTOXY-BENZALDEHYDE
CAS No.
18962-07-7
Chemical Name
4-ISOBUTOXY-BENZALDEHYDE
Synonyms
AKOS B000265;FeBuxostat Impurity 34;4-Isobutoxy-benzaldehyd;p-isobutoxybenzaldehyde;p-iso-Butoxy-benzaldehyd;4-(i-butoxy)benzaldehyde;4-ISOBUTOXY-BENZALDEHYDE;Benzaldehyde, 4-(2-methylpropoxy)-;2-(3-cyano-2-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
CBNumber
CB5150382
Molecular Formula
C11H14O2
Formula Weight
178.23
MOL File
18962-07-7.mol
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4-ISOBUTOXY-BENZALDEHYDE Property

Melting point:
155℃
Boiling point:
74°C/0.08mm
Density 
1.018±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.5344 (589.3 nm 20℃)
Flash point:
118.9±13.4℃
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Oil
color 
Pale Yellow
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2912490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I789258
Product name
4-Isobutoxybenzaldehyde
Packaging
25mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
028458
Product name
4-Isobutoxybenzaldehyde
Packaging
500mg
Price
$26
Updated
2021/12/16
AK Scientific
Product number
6382AD
Product name
4-Isobutoxybenzaldehyde
Packaging
25g
Price
$545
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0068947
Product name
4-(2-METHYLPROPOXY)BENZALDEHYDE
Purity
95.00%
Packaging
1G
Price
$692.46
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0068947
Product name
4-(2-METHYLPROPOXY)BENZALDEHYDE
Purity
95.00%
Packaging
2.5G
Price
$932.6
Updated
2021/12/16
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4-ISOBUTOXY-BENZALDEHYDE Chemical Properties,Usage,Production

Uses

4-Isobutoxybenzaldehyde to treat neurodegenerative diseases.

Synthesis

78-77-3

123-08-0

18962-07-7

Step 2: Preparation of 4-isobutoxybenzaldehyde (Compound XIII) 4-Hydroxybenzaldehyde (10 g, 0.082 mol), potassium carbonate (33.95 g, 0.246 mol) and potassium iodide (1.36 g, 0.008 mol) were suspended in N,N-dimethylformamide (50 mL). Isobutyl bromide (26.7 mL, 0.246 mol) was added to the suspension and the reaction was subsequently heated at 70 °C and protected by nitrogen for 3 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with 150 mL of water and then extracted with 300 mL of ethyl acetate. The organic phase was washed five times with 150 mL of 10% NaCl solution, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 14.3 g (98% yield) of the yellow oily product 4-isobutoxybenzaldehyde (Compound XIII).

References

[1] Patent: US2018/37549, 2018, A1. Location in patent: Paragraph 0151
[2] Patent: CN105418460, 2016, A. Location in patent: Paragraph 0053; 0056; 0057; 0058; 0059
[3] Patent: CN108358817, 2018, A. Location in patent: Paragraph 0055; 0056; 0057
[4] Russian Journal of General Chemistry, 2005, vol. 75, # 7, p. 1113 - 1124
[5] Patent: WO2006/36874, 2006, A1. Location in patent: Page/Page column 21

4-ISOBUTOXY-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-ISOBUTOXY-BENZALDEHYDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
Country
China
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96815
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76
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
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China
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
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China
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35896
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Adamas Reagent, Ltd.
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400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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han_yajun@dctc.daicel.com
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China
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Wuhan Haizheng Industry & Trade Development Co. Ltd
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Bide Pharmatech Ltd.
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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China
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15178
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Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
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xingui2022@126.com
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China
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Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
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sales@chalf-pharm.com
Country
China
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View Lastest Price from 4-ISOBUTOXY-BENZALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Isobutoxybenzaldehyde 18962-07-7
Price
US $22.00-88.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50kg
Release date
2025-06-25
Career Henan Chemical Co
Product
4-ISOBUTOXY-BENZALDEHYDE 18962-07-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 428
Release date
2019-09-01