Febuxostat-d9

Product Name: Febuxostat-d9
CAS No.: 1246819-50-0
Chemical Name: Febuxostat-d9
Synonyms: TMX 67-d9;TEI 6720-d9;Febuxostat-d;Febuxostat-d9;[2H9]-Febuxostat;Dapagliflozin Impurity 138;Febuxostat-d9 (2-methylpropoxy-d9);2-(3-Cyano-4-isobutyloxyphenyl-d9)-4-Methyl-5-thiazolecarboxylic Acid;2-[3-Cyano-4-(2-Methylpropoxy-d9)phenyl]-4-Methyl-5-thiazolecarboxylic Acid;Febuxostat D9Q: What is Febuxostat D9 Q: What is the CAS Number of Febuxostat D9 Q: What is the storage condition of Febuxostat D9 Q: What are the applications of Febuxostat D9
CBNumber: CB22508843
Molecular Formula: C16H16N2O3S
Formula Weight: 316.37484
MOL File: 1246819-50-0.mol

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Febuxostat-d9 Property

Melting point:: >201°C (dec.)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25033
Product name: Febuxostat-d9
Purity: ≥99% deuterated forms (d1-d9)
Packaging: 1mg
Price: $261
Updated: 2024/03/01

TRC

Product number: F229002
Product name: Febuxostat-d9
Packaging: 1mg
Price: $160
Updated: 2021/12/16

AK Scientific

Product number: 3669AH
Product name: Febuxostat-D9
Packaging: 1mg
Price: $471
Updated: 2021/12/16

aablocks

Product number: AA009CF5
Product name: Febuxostat-d9
Purity: ≥99%deuteratedforms(d<sub>1</sub>-d<sub>9</sub>)
Packaging: 1mg
Price: $394
Updated: 2021/12/16

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Febuxostat-d9 Chemical Properties,Usage,Production

Description

Febuxostat-d₉ is intended for use as an internal standard for the quantification of febuxostat by GC- or LC-MS. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. It inhibits bovine milk xanthine oxidase as well as mouse and rat liver xanthine oxidase/xanthine dehydrogenase (IC₅₀s = 1.4, 1.8, and 2.2 nM, respectively). It is 10-30 times more potent than the hypoxanthine analog allopurinol (; K_is = 0.7 nM and 0.7 μM, respectively). Febuxostat decreases the serum level of urate in a potassium oxonate rat model of hyperuricemia (ED₅₀ = 1.5 mg/kg). It reduces hepatic macrovesicular steatosis in mice fed a high-fat diet containing trans fatty acids when administered at a dose of 1 mg/kg per day. Febuxostat (0.75 mg/kg) also increases CNS expression of glutamate oxaloacetate transaminase 2 (GOT2) and improves neurological symptoms in a mouse model of secondary progressive experimental autoimmune encephalomyelitis (EAE). Formulations containing febuxostat have been used in the treatment of symptomatic hyperuricemia in patients with gout.

Uses

Febuxostat-d9 is a Labeled compound, intended for use as an internal standard for the quantification of Febuxostat by GC- or LC-mass spectrometry.

Uses

Labelled Febuxostat (F229000). Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.

Febuxostat-d9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Febuxostat-d9 Suppliers

Canada 2 China 39 India 4 United States 3 Global 48

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Artis Biotech Co. Ltd.

Tel: 19138486554 18582380095
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
ProdList: 3066
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

Clearsynth Canada Inc.

Tel: +1.415.685.4395
Fax: +1.415.685.4395
Email: enquiry@clearsynth.com
Country: Canada
ProdList: 912
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Chengdu Novel Biomedical Co., Ltd.

Tel: 028-85255396 18302801538
Fax: 028-85255396
Email: cdnovell@163.com
Country: China
ProdList: 2238
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

1246819-50-0, Febuxostat-d9Related Search:

Febuxostat 2-HYDROXY-THIOBENZAMIDE 2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid 2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Febuxostat impurity 37 FeBuxostat Impurity 33 3-Cyano-4-isobutoxybenzoic acid ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE 4-ISOBUTOXY-BENZALDEHYDE 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 6 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate Febuxostat Impurity 8 Febuxostat Impurity 14 Febuxostat Bromo Impurity

Febuxostat-d9

2-(3-Cyano-4-isobutyloxyphenyl-d9)-4-Methyl-5-thiazolecarboxylic Acid

2-[3-Cyano-4-(2-Methylpropoxy-d9)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

TEI 6720-d9

TMX 67-d9

[2H9]-Febuxostat

Febuxostat-d9 (2-methylpropoxy-d9)

Febuxostat D9Q: What is Febuxostat D9 Q: What is the CAS Number of Febuxostat D9 Q: What is the storage condition of Febuxostat D9 Q: What are the applications of Febuxostat D9

Dapagliflozin Impurity 138

Febuxostat-d

1246819-50-0

C16H7D9N2O3S

Inhibitors

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Pharmaceuticals

Heterocycles