5-BROMO-2-(DIMETHYLAMINO)PYRAZINE

Product Name: 5-BROMO-2-(DIMETHYLAMINO)PYRAZINE
CAS No.: 446286-94-8
Chemical Name: 5-BROMO-2-(DIMETHYLAMINO)PYRAZINE
Synonyms: 2-BROMO-5-DIMETHYLAMINOPYRAZINE;5-BROMO-2-(DIMETHYLAMINO)PYRAZINE;(5-BROMO-2-PYRAZINYL)DIMETHYLAMINE;5-bromo-N,N-dimethylpyrazin-2-amine;2-Pyrazinamine, 5-bromo-N,N-dimethyl-;(5-BroMo-pyrazin-2-yl)-diMethyl-aMine
CBNumber: CB51504058
Molecular Formula: C6H8BrN3
Formula Weight: 202.05
MOL File: 446286-94-8.mol

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5-BROMO-2-(DIMETHYLAMINO)PYRAZINE Property

Boiling point:: 265.2±35.0 °C(Predicted)
Density: 1.553±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 1.74±0.10(Predicted)
Appearance: Light yellow to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB139368
Product name: 5-Bromo-N,N-dimethylpyrazin-2-amine
Packaging: 500mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139368
Product name: 5-Bromo-N,N-dimethylpyrazin-2-amine
Packaging: 1g
Price: $91
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139368
Product name: 5-Bromo-N,N-dimethylpyrazin-2-amine
Packaging: 2g
Price: $158
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139368
Product name: 5-Bromo-N,N-dimethylpyrazin-2-amine
Packaging: 5G
Price: $316
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0356231
Product name: (5-BROMO-2-PYRAZINYL)DIMETHYLAMINE
Purity: 95.00%
Packaging: 5MG
Price: $503.05
Updated: 2021/12/16

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5-BROMO-2-(DIMETHYLAMINO)PYRAZINE Chemical Properties,Usage,Production

Synthesis

59489-71-3

74-88-4

446286-94-8

2-Amino-5-bromopyrazine (1,170 mg, 6.72 mmol) was dissolved in tetrahydrofuran (THF, 100 mL) and iodomethane (CH3I, 1.2 mL, 19.5 mmol) was added. The reaction mixture was cooled to 0 °C, 60% sodium hydride (NaH, 1.5 g, 37.5 mmol) was added slowly and stirred at this temperature for 5 hours. Upon completion of the reaction, a small amount of methanol was added to quench the excess sodium hydride, followed by the addition of water (10 mL). The reaction mixture was extracted with ethyl acetate (3 x 200 mL), the organic layers were combined and dried over anhydrous sodium sulfate. The organic layer was concentrated under reduced pressure and the resulting crude product was purified by column chromatography [silica gel 48.5 g; eluent: hexane-ethyl acetate (1:1)] to afford 5-bromo-2-(dimethylamino)pyrazine (1,096 mg, 5.4 mmol, 80% yield) as a light yellow powdery solid.

References

[1] Patent: JP2015/193584, 2015, A. Location in patent: Paragraph 0080; 0081

5-BROMO-2-(DIMETHYLAMINO)PYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-(DIMETHYLAMINO)PYRAZINE Suppliers

China 40 Czech Republic 1 India 1 United Kingdom 1 United States 1 Global 44

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446286-94-8, 5-BROMO-2-(DIMETHYLAMINO)PYRAZINERelated Search:

5-BROMO-2-(PIPERIDIN-1-YL)PYRIMIDINE 5-BROMO-N-METHYLPYRIDIN-2-AMINE 5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE 4-PyriMidinecarboxylic acid, 5-broMo-2-(Methylthio)-, ethyl ester 5-BroMo-2,4-dichloro-7H-pyrrolo[2,3-d]pyriMidine 5-BROMO-2-(PIPERAZIN-1-YL)-3-METHYLPYRIDINE 5-BROMO-2-(2,2,2-TRIFLUORO-ETHOXY)-PYRIDINE 3,5-DIBROMO-N,N-DIMETHYLPYRAZINAMINE 2-BROMO-5-(PIPERAZIN-1-YL)PYRAZINE 4-(5-BROMO-2-PYRAZINYL)MORPHOLINE 5-BROMO-2-(DIMETHYLAMINO)PYRAZINE 2-BROMO-5-(4-METHYLPIPERAZIN-1-YL)PYRAZINE 5-BROMO-2-(DIETHYLAMINO)PYRAZINE 2-[1-(5-BROMO-6-CHLOROPYRAZIN-2-YL)PIPERIDIN-4-YL]-1H-ISOINDOLE-1,3(2H)-DIONE TERT-BUTYL [1-(5-BROMO-6-CHLOROPYRAZIN-2-YL)PIPERIDIN-4-YL]CARBAMATE 3-(5-BROMOPYRAZIN-2-YL)-3,9-DIAZASPIRO [5.5]UNDECANE TERT-BUTYL 4-[5-BROMO-6-(3-CHLOROPYRIDIN-4-YL)PYRAZIN-2-YL]PIPERAZINE-1-CARBOXYLATE TERT-BUTYL 4-(5-BROMO-6-CHLOROPYRAZIN-2-YL)PIPERAZINE-1-CARBOXYLATE

(5-BROMO-2-PYRAZINYL)DIMETHYLAMINE

5-BROMO-2-(DIMETHYLAMINO)PYRAZINE

5-bromo-N,N-dimethylpyrazin-2-amine

2-BROMO-5-DIMETHYLAMINOPYRAZINE

(5-BroMo-pyrazin-2-yl)-diMethyl-aMine

2-Pyrazinamine, 5-bromo-N,N-dimethyl-

446286-94-8