ChemicalBook > CAS DataBase List > 5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE

Product Name
5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
CAS No.
129075-49-6
Chemical Name
5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
Synonyms
5-Methoxy-3,4-dihydroisoquinolin-1(2H);5-Methoxy-3,4-dihydro-2H-isoquinolin-1-one;5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE;1(2H)-Isoquinolinone, 3,4-dihydro-5-methoxy-;5-Methoxy-1,2,3,4-tetrahydroisoquinolin-1-one
CBNumber
CB51508137
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
129075-49-6.mol
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5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Property

storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M269828
Product name
5-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
Packaging
10mg
Price
$45
Updated
2021/12/16
Ark Pharm
Product number
P000285594
Product name
5-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
Purity
95+%
Packaging
100mg
Price
$138
Updated
2021/12/16
AK Scientific
Product number
3249AJ
Product name
5-Methoxy-3,4-dihydro-2H-isoquinolin-1-one
Packaging
1g
Price
$448
Updated
2021/12/16
Ark Pharm
Product number
P000285594
Product name
5-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
Purity
95+%
Packaging
250mg
Price
$208
Updated
2021/12/16
Ark Pharm
Product number
P000285594
Product name
5-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
Purity
95+%
Packaging
1g
Price
$519
Updated
2021/12/16
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5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Chemical Properties,Usage,Production

Synthesis

13336-31-7

129075-49-6

GENERAL METHOD: 4-methoxy-1-indanone (1.5 mmol) was dissolved in 37% hydrochloric acid (5 mL) at 0°C and sodium azide (NaN3, 0.2 g, 3.0 mmol) was added slowly. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was poured into ice water and adjusted to alkaline with sodium carbonate (Na2CO3). The aqueous phase was extracted with ethyl acetate (3 x 10 mL). The organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography with the eluent being a solvent mixture of dichloromethane (CH2Cl2) and ethyl acetate (AcOEt) (9:1, v/v).

References

[1] European Journal of Medicinal Chemistry, 2013, vol. 69, p. 920 - 930

5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE Suppliers

Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
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View Lastest Price from 5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE manufacturers

Career Henan Chemical Co
Product
5-methoxy-3,4-dihydro-2H-isoquinolin-1-one 129075-49-6
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-29

129075-49-6, 5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONERelated Search:


  • 5-METHOXY-3,4-DIHYDRO-1(2H)-ISOQUINOLINONE
  • 5-Methoxy-1,2,3,4-tetrahydroisoquinolin-1-one
  • 5-Methoxy-3,4-dihydro-2H-isoquinolin-1-one
  • 5-Methoxy-3,4-dihydroisoquinolin-1(2H)
  • 1(2H)-Isoquinolinone, 3,4-dihydro-5-methoxy-
  • 129075-49-6