ChemicalBook > CAS DataBase List > 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Product Name: 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
CAS No.: 122450-96-8
Chemical Name: 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Synonyms: 7-Bromo-4H-pyrido[3,2-b][1,4]oxazin-3-one;7-BROMO-2H,4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE;7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one;7-bromo-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 7-bromo-;3-Oxo-3,4-dihydro-2H-1-oxa-4,5-diaza-7-broMo-naphthalene
CBNumber: CB51515836
Molecular Formula: C7H5BrN2O2
Formula Weight: 229.03
MOL File: 122450-96-8.mol

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7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one Property

Boiling point:: 403.9±45.0 °C(Predicted)
Density: 1.772
storage temp.: Sealed in dry,Room Temperature
pka: 9.98±0.20(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B122450
Product name: 7-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB141960
Product name: 7-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 100mg
Price: $66
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB141960
Product name: 7-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 250mg
Price: $132.5
Updated: 2021/12/16

AK Scientific

Product number: 4258AA
Product name: 7-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 1g
Price: $157
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB141960
Product name: 7-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Packaging: 500mg
Price: $230
Updated: 2021/12/16

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7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one Chemical Properties,Usage,Production

Synthesis

20348-09-8

122450-96-8

General procedure for the synthesis of 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones from 2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones: to 2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones (1 g, 6.66 mmol) of N,N-dimethylformamide (DMF. 30 mL) solution was slowly added bromine (0.480 mL, 9.32 mmol) dropwise. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, deionized water was added to induce precipitate formation and the precipitate was collected by filtration. The resulting solid was dried overnight in a freeze dryer to afford 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (1.16 g, 76% yield). The product was characterized by 1H NMR (DMSO-d6): δ 11.43 (s, 1H), 8.04 (d, J = 2.0 Hz, 1H), 7.65 (d, J = 2.0 Hz, 1H), 4.67 (s, 2H).

References

[1] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 2, p. 133 - 142
[2] Patent: WO2009/100536, 2009, A1. Location in patent: Page/Page column 93-94
[3] Patent: WO2006/113432, 2006, A2. Location in patent: Page/Page column 56-57
[4] Patent: US4906629, 1990, A
[5] Patent: US4822794, 1989, A

7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one Suppliers

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122450-96-8, 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-oneRelated Search:

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