2-amino-5-bromopyridin-3-ol
- Product Name
- 2-amino-5-bromopyridin-3-ol
- CAS No.
- 39903-01-0
- Chemical Name
- 2-amino-5-bromopyridin-3-ol
- Synonyms
- 2-Amino-5-bromo-3-hydroxypyridine;EOS-61763;2-Amino-5-bromo-3-pyridinol;2-amino-5-bromopyridin-3-ol;3-Pyridinol, 2-aMino-5-broMo-;3Hydroxy-2-aMino-5-broMopyridine;5-Bromo-3-hydroxy-2-aminopyridine;2-Hydroxy-3-amino-5-bromopyridine;2(1H)-Pyridinone,3-amino-5-bromo-;2-Amino-5-bromo-3-hydroxypyridine >
- CBNumber
- CB7947708
- Molecular Formula
- C5H5BrN2O
- Formula Weight
- 189.01
- MOL File
- 39903-01-0.mol
2-amino-5-bromopyridin-3-ol Property
- Melting point:
- 204-207℃
- Boiling point:
- 368.7±42.0 °C(Predicted)
- Density
- 1.898
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 11.48±0.10(Predicted)
- form
- Solid
- color
- Off-white
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C5H5BrN2O/c6-3-1-4(9)5(7)8-2-3/h1-2,9H,(H2,7,8)
- InChIKey
- YQADLKDQAXAIKW-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(Br)C=C1O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A2673
- Product name
- 2-Amino-5-bromo-3-hydroxypyridine
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- A2673
- Product name
- 2-Amino-5-bromo-3-hydroxypyridine
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $91
- Updated
- 2025/07/31
- Product number
- A602098
- Product name
- 2-Amino-5-bromopyridin-3-ol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA45105
- Product name
- 2-Amino-3-hydroxy-5-bromopyridine
- Packaging
- 5G
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 072249
- Product name
- 2-Amino-5-bromo-3-pyridinol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
2-amino-5-bromopyridin-3-ol Chemical Properties,Usage,Production
Uses
2-Amino-5-bromo-3-hydroxypyridine is used as an organic chemical synthesis intermediate.
Synthesis
21594-52-5
39903-01-0
General procedure for the synthesis of 3-hydroxy-2-amino-5-bromopyridine from 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one: 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one (21.5 g, 100 mmol) was suspended in 2N NaOH solution (250 mL, 500 mmol). The mixture was refluxed and reacted overnight until a clarified solution was formed. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently neutralized with acid to a pH of about 7. During this process, the release of large amounts of CO2 gas as well as the formation of a precipitate was observed. The precipitate was collected by filtration, washed with water and dried under high vacuum to give the final 2-amino-5-bromopyridin-3-ol as an off-white solid (17.8 g, 98% yield).
References
[1] Patent: US2006/46991, 2006, A1. Location in patent: Page/Page column 33-34
[2] Patent: WO2006/21886, 2006, A1. Location in patent: Page/Page column 64; 65
[3] Heterocycles, 2001, vol. 55, # 7, p. 1329 - 1345
[4] Heterocycles, 1995, vol. 41, # 12, p. 2799 - 2810
[5] Tetrahedron Letters, 2014, vol. 55, # 9, p. 1528 - 1531
2-amino-5-bromopyridin-3-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-amino-5-bromopyridin-3-ol manufacturers
- Product
- 2-amino-5-bromopyridin-3-ol 39903-01-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-19
- Product
- 2-Hydroxy-3-amino-5-bromopyridine 39903-01-0
- Price
- US $480.00/kg
- Min. Order
- 1kg
- Purity
- 98 %
- Supply Ability
- 8Ton
- Release date
- 2024-05-15
- Product
- 2-Hydroxy-3-amino-5-bromopyridine 39903-01-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-24