ChemicalBook > CAS DataBase List > 2-amino-5-bromopyridin-3-ol

2-amino-5-bromopyridin-3-ol

Product Name
2-amino-5-bromopyridin-3-ol
CAS No.
39903-01-0
Chemical Name
2-amino-5-bromopyridin-3-ol
Synonyms
2-Amino-5-bromo-3-hydroxypyridine;EOS-61763;2-Amino-5-bromo-3-pyridinol;2-amino-5-bromopyridin-3-ol;3-Pyridinol, 2-aMino-5-broMo-;3Hydroxy-2-aMino-5-broMopyridine;5-Bromo-3-hydroxy-2-aminopyridine;2-Hydroxy-3-amino-5-bromopyridine;2(1H)-Pyridinone,3-amino-5-bromo-;2-Amino-5-bromo-3-hydroxypyridine >
CBNumber
CB7947708
Molecular Formula
C5H5BrN2O
Formula Weight
189.01
MOL File
39903-01-0.mol
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2-amino-5-bromopyridin-3-ol Property

Melting point:
204-207℃
Boiling point:
368.7±42.0 °C(Predicted)
Density 
1.898
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
11.48±0.10(Predicted)
form 
Solid
color 
Off-white
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C5H5BrN2O/c6-3-1-4(9)5(7)8-2-3/h1-2,9H,(H2,7,8)
InChIKey
YQADLKDQAXAIKW-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Br)C=C1O
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
36/37
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2673
Product name
2-Amino-5-bromo-3-hydroxypyridine
Purity
>98.0%(HPLC)
Packaging
1g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
A2673
Product name
2-Amino-5-bromo-3-hydroxypyridine
Purity
>98.0%(HPLC)
Packaging
5g
Price
$91
Updated
2025/07/31
TRC
Product number
A602098
Product name
2-Amino-5-bromopyridin-3-ol
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA45105
Product name
2-Amino-3-hydroxy-5-bromopyridine
Packaging
5G
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
072249
Product name
2-Amino-5-bromo-3-pyridinol
Purity
95+%
Packaging
1g
Price
$15
Updated
2021/12/16
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2-amino-5-bromopyridin-3-ol Chemical Properties,Usage,Production

Uses

2-Amino-5-bromo-3-hydroxypyridine is used as an organic chemical synthesis intermediate.

Synthesis

21594-52-5

39903-01-0

General procedure for the synthesis of 3-hydroxy-2-amino-5-bromopyridine from 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one: 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one (21.5 g, 100 mmol) was suspended in 2N NaOH solution (250 mL, 500 mmol). The mixture was refluxed and reacted overnight until a clarified solution was formed. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently neutralized with acid to a pH of about 7. During this process, the release of large amounts of CO2 gas as well as the formation of a precipitate was observed. The precipitate was collected by filtration, washed with water and dried under high vacuum to give the final 2-amino-5-bromopyridin-3-ol as an off-white solid (17.8 g, 98% yield).

References

[1] Patent: US2006/46991, 2006, A1. Location in patent: Page/Page column 33-34
[2] Patent: WO2006/21886, 2006, A1. Location in patent: Page/Page column 64; 65
[3] Heterocycles, 2001, vol. 55, # 7, p. 1329 - 1345
[4] Heterocycles, 1995, vol. 41, # 12, p. 2799 - 2810
[5] Tetrahedron Letters, 2014, vol. 55, # 9, p. 1528 - 1531

2-amino-5-bromopyridin-3-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-amino-5-bromopyridin-3-ol manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-amino-5-bromopyridin-3-ol 39903-01-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-03-19
Xi'an Yutbon Pharmaceutical Technology Co., Ltd
Product
2-Hydroxy-3-amino-5-bromopyridine 39903-01-0
Price
US $480.00/kg
Min. Order
1kg
Purity
98 %
Supply Ability
8Ton
Release date
2024-05-15
Dideu Industries Group Limited
Product
2-Hydroxy-3-amino-5-bromopyridine 39903-01-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-24

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