3-Bromo-5-ethoxypyridine

Product Name: 3-Bromo-5-ethoxypyridine
CAS No.: 17117-17-8
Chemical Name: 3-Bromo-5-ethoxypyridine
Synonyms: 5-bromo-3-ethoxypyridine;Pyridine, 3-broMo-5-ethoxy-
CBNumber: CB5967407
Molecular Formula: C7H8BrNO
Formula Weight: 202.05
MOL File: 17117-17-8.mol

More

Less

3-Bromo-5-ethoxypyridine Property

Melting point:: 9°C(lit.)
Boiling point:: 240°C(lit.)
refractive index: 1.5540 to 1.5580
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
color: Colorless to Light orange to Yellow

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5000
Product name: 3-Bromo-5-ethoxypyridine
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $81
Updated: 2025/07/31

TCI Chemical

Product number: B5000
Product name: 3-Bromo-5-ethoxypyridine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $322
Updated: 2025/07/31

TRC

Product number: B696073
Product name: 3-Bromo-5-ethoxypyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB153707
Product name: 3-Bromo-5-ethoxypyridine
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB153707
Product name: 3-Bromo-5-ethoxypyridine
Packaging: 1g
Price: $100
Updated: 2021/12/16

More

Less

3-Bromo-5-ethoxypyridine Chemical Properties,Usage,Production

Synthesis

625-92-3

64-17-5

17117-17-8

Sodium metal (4.60 g, 200 mmol) was added in batches to anhydrous ethanol (100 mL) under nitrogen protection, keeping the reaction temperature at 0-5 °C. The mixture was stirred to slowly warm up to room temperature over 18 hours. Subsequently, 3,5-dibromopyridine (31.5 g, 133 mmol) and N,N-dimethylformamide (DMF, 100 mL) were added to the reaction system. The reaction mixture was heated to 70 °C with continuous stirring for 48 hours. After completion of the reaction, the brown mixture was cooled to room temperature, slowly poured into water (600 mL) and extracted with ether (3 x 500 mL). The ether extracts were combined, dried with anhydrous sodium sulfate, filtered and concentrated by rotary evaporator. The final product was purified by vacuum distillation to give 22.85 g (85.0% yield) of 5-bromo-3-ethoxypyridine as an oil with a boiling point of 89-90 °C (2.8 mmHg). A boiling point of 111 °C (5 mmHg) has been reported in the literature (see K. Clarke et al., J. Chem. Soc. 1885 (1960)).

References

[1] Patent: WO2006/23630, 2006, A2. Location in patent: Page/Page column 60
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 14, p. 4126 - 4141
[3] Patent: WO2010/96389, 2010, A1. Location in patent: Page/Page column 37; 39
[4] Patent: WO2010/135014, 2010, A1. Location in patent: Page/Page column 45-47
[5] Patent: WO2011/87776, 2011, A1. Location in patent: Page/Page column 48; 51

3-Bromo-5-ethoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Bromo-5-ethoxypyridine Suppliers

Americas 1 China 70 Europe 1 France 2 Germany 3 India 8 Japan 1 The Netherlands 1 United Kingdom 3 United States 13 Global 103

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
Advantage: 58

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 3991
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

17117-17-8, 3-Bromo-5-ethoxypyridineRelated Search:

5-Bromo-2-ethoxypyridine 4-BROMO-2-ETHOXYPYRIDINE 2-Amino-5-bromo-3-benzloxypyridine 3-(BENZYLOXY)-5-BROMOPYRIDINE 3-Bromo-5-ethoxypyridine 7-Bromo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine 7-bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 5-BROMO-3-(2-HYDROXYETHOXY)-PYRIDINE 7-BROMO-4-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,2-B][1,4]OXAZINE 5-BROMO-2-IODOPYRIDIN-3-YL ACETATE 3-Bromo-5-(4-methoxybenzyloxy)pyridine SPECS AC-907/25004644 5-BROMO-3-(1-ETHYLPROPOXY)-6-[2-METHOXY-4-(TRIFLUOROMETHOXY)PHENYL]-N-METHYLPYRIDIN-2-AMINE 5-BROMO-6-(2,4-DIMETHOXYPHENYL)-3-(1-ETHYLPROPOXY)-N-METHYLPYRIDIN-2-AMINE METHYL 5-[3-BROMO-5-(1-ETHYLPROPOXY)-6-(METHYLAMINO)PYRIDIN-2-YL]-2,4-DIMETHOXYBENZOATE SPECS AO-801/41077515 5-BROMO-3-(1-ETHYLPROPOXY)PYRIDIN-2-AMINE

5-bromo-3-ethoxypyridine

Pyridine, 3-broMo-5-ethoxy-

17117-17-8