ChemicalBook > CAS DataBase List > 5-METHYLCYTOSINE

5-METHYLCYTOSINE

Product Name
5-METHYLCYTOSINE
CAS No.
554-01-8
Chemical Name
5-METHYLCYTOSINE
Synonyms
4-Amino-5-methylpyrimidin-2(1H)-one;5-methylcytosin;5-METHYLCYTOSINE;Cytosine, 5-methyl-;5-Methylcytosine,>96%;5-Methylcytosine (~90%);5-Methylcytosine, 97%, 97%;5-METHYLCYTOSINE USP/EP/BP;4-Amino-5-methyl-2-pyrimidinol;4-amino-5-methyl-3H-pyrimidin-2-one
CBNumber
CB5154906
Molecular Formula
C5H7N3O
Formula Weight
125.13
MOL File
554-01-8.mol
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5-METHYLCYTOSINE Property

Melting point:
270°C (rough estimate)
Boiling point:
232.57°C (rough estimate)
Density 
1.2602 (rough estimate)
refractive index 
1.6510 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Methanol (Sparingly, Heated)
pka
9.05±0.10(Predicted)
form 
Crystalline
color 
White to Off-White
Water Solubility 
Soluble in water.
Merck 
14,6050
CAS DataBase Reference
554-01-8(CAS DataBase Reference)
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Safety

RTECS 
UW7362350
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Alfa Aesar
Product number
043492
Product name
5-Methylcytosine, 97%
Packaging
100mg
Price
$104
Updated
2024/03/01
Alfa Aesar
Product number
043492
Product name
5-Methylcytosine, 97%
Packaging
500mg
Price
$342.65
Updated
2024/03/01
Usbiological
Product number
C9111
Product name
Cytosine, 5-Methyl
Packaging
50ug
Price
$369
Updated
2021/12/16
TRC
Product number
M294873
Product name
5-Methylcytosine(~90%)
Packaging
1g
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-W008091
Product name
5-Methylcytosine
Purity
99.82%
Packaging
10g
Price
$52
Updated
2021/12/16
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5-METHYLCYTOSINE Chemical Properties,Usage,Production

Chemical Properties

Crystals in prisms from water.

Uses

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.

Definition

ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.

Purification Methods

Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.]

5-METHYLCYTOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHYLCYTOSINE Suppliers

Canada 1 China 191 Europe 3 Germany 2 India 5 Japan 1 Slovakia 1 South Korea 1 United Kingdom 5 United States 16 Global 226
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View Lastest Price from 5-METHYLCYTOSINE manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
5-METHYLCYTOSINE 554-01-8
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99
Supply Ability
20tons
Release date
2024-02-06
Hebei Duling International Trade Co. LTD
Product
5-Methylcytosine 554-01-8
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2022-11-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-methylcytosine 554-01-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

554-01-8, 5-METHYLCYTOSINERelated Search:

5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5-METHYLCYTIDINE 5-(TRIFLUOROMETHYL)-2'-DEOXYCYTIDINE 5-CARBOXYCYTOSINE 5-METHYLCYTOSINE 1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine 2'-C-Methylcytidine 2-O-Methylcytosine 5-METHYLCYTOSINE HCL,5-METHYLCYTOSINE HYDROCHLORIDE 98%,5-METHYLCYTOSINE HYDROCHLORIDE,5-Methylcytosine hydrochloride ,98% 5-HYDROXYMETHYLCYTOSINE N4-Methylcytosine ,98%,N4-Methylcytosine Cytosine FLUORESCEIN-12-DCTP BIOTIN-11-DDCTP N4-BENZOYL-5-METHYLDEOXYCYTIDINE 5'-METHYL-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE TRILITHIUM SALT 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE 3-METHYLCYTOSINE HYDROCHLORIDE

  • 4-Amino-5-methyl-2-pyrimidinol
  • Cytosine, 5-methyl-
  • 5-Methylcytosine,>96%
  • 2(1H)-Pyrimidinone, 4-amino-5-methyl- (9CI)
  • 4-amino-5-methyl-3H-pyrimidin-2-one
  • 5-METHYLCYTOSINE
  • 2(1H)-Pyrimidinone, 6-amino-5-methyl-
  • 2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine
  • 2(1H)-Oxo-4-amino-5-methylpyrimidine
  • 2-Hydroxy-4-amino-5-methylpyrimidine
  • 4-Amino-5-methyl-1,2-dihydropyrimidine-2-one
  • 4-Amino-5-methylpyrimidin-2(1H)-one
  • 4(6)-AMino-2-hydroxy-5-MethylpyriMidine
  • 4-AMino-5-Methyl-2(1H)pyriMidinone
  • 4-aMino-5-Methyl-1,2-dihydropyriMidin-2-one
  • 5-methylcytosin
  • 5-Methylcytosine, 97%, 97%
  • 5-Methylcytosine (~90%)
  • 5-METHYLCYTOSINE USP/EP/BP
  • 554-01-8
  • Nucleic acids
  • Pyrimidines
  • PYRIMIDINE
  • Elisa Kit-Rat Elisa Kit