2'-C-Methylcytidine
- Product Name
- 2'-C-Methylcytidine
- CAS No.
- 20724-73-6
- Chemical Name
- 2'-C-Methylcytidine
- Synonyms
- NM-107;CS-2055;-C-Methylcytidine;2''-METHYLCYTIDINE;2'-C-METHYLCYTIDINE;2’-C-Methyl cytidine;2'-CMethyl-D-cytidine;2’-β-C-Methylcytidine;Cytidine, 2'-C-methyl-;2’-b-C-Methyl cytidine
- CBNumber
- CB5732016
- Molecular Formula
- C10H15N3O5
- Formula Weight
- 257.24
- MOL File
- 20724-73-6.mol
2'-C-Methylcytidine Property
- Melting point:
- 243-245°C
- Boiling point:
- 523.9±60.0 °C(Predicted)
- Density
- 1.72±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: >20mg/mL
- pka
- 13.53±0.70(Predicted)
- form
- powder
- color
- white to off-white
- InChIKey
- PPUDLEUZKVJXSZ-VPCXQMTMSA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M4949
- Product name
- 2’-C-Methylcytidine
- Purity
- ≥95% (HPLC), powder
- Packaging
- 5mg
- Price
- $97.9
- Updated
- 2024/03/01
- Product number
- M4949
- Product name
- 2’-C-Methylcytidine
- Purity
- ≥95% (HPLC), powder
- Packaging
- 25mg
- Price
- $388
- Updated
- 2024/03/01
- Product number
- 22887
- Product name
- 2'-C-Methylcytidine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 22887
- Product name
- 2'-C-Methylcytidine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 22887
- Product name
- 2'-C-Methylcytidine
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $336
- Updated
- 2024/03/01
2'-C-Methylcytidine Chemical Properties,Usage,Production
Description
2''-C-Methylcytidine (2CMC) is a ribonucleoside with broad-spectrum antiviral activity. It reduces the number of viral plaques in BHK-21 cells infected with dengue type 2, reovirus type 1, West Nile, and yellow fever RNA viruses with EC50 values of 95, 26, 80, and 75 μM, respectively. 2CMC inhibits hepatitis C virus (HCV) replication (EC50 = 2.2 μM in a replicon assay) and protects MDBK cells from infection with bovine virus diarrhea virus (BVDV; EC50 = 2.2 μM) and human coronavirus (HCoV; EC50 = 90 μM). It also reduces infectious virus yield in BHK-21 cells infected with foot-and-mouth disease virus (FMDV; EC50 = 6.4 μM) and swine vesicular disease virus (SVDV; EC50 = 45.2 μM). In vivo, 2CMC reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection.
Chemical Properties
White to Off-White Powder
Uses
2’-C-Methyl Cytidine (cas# 20724-73-6) is a compound useful in organic synthesis.
Biochem/physiol Actions
2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.
2'-C-Methylcytidine Preparation Products And Raw materials
Raw materials
Preparation Products
2'-C-Methylcytidine Suppliers
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View Lastest Price from 2'-C-Methylcytidine manufacturers
- Product
- 2'-C-methylCytidine 20724-73-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100g
- Release date
- 2024-06-03
- Product
- 2'-C-Methylcytidine 20724-73-6
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-08-05