2'-C-Methylcytidine

ChemicalBook > CAS DataBase List > 2'-C-Methylcytidine

Product Name: 2'-C-Methylcytidine
CAS No.: 20724-73-6
Chemical Name: 2'-C-Methylcytidine
Synonyms: NM-107;CS-2055;-C-Methylcytidine;2''-METHYLCYTIDINE;2'-C-METHYLCYTIDINE;2’-C-Methyl cytidine;2'-CMethyl-D-cytidine;2’-β-C-Methylcytidine;Cytidine, 2'-C-methyl-;2’-b-C-Methyl cytidine
CBNumber: CB5732016
Molecular Formula: C10H15N3O5
Formula Weight: 257.24
MOL File: 20724-73-6.mol

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2'-C-Methylcytidine Property

Melting point:: 243-245°C
Boiling point:: 523.9±60.0 °C(Predicted)
Density: 1.72±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: H2O: >20mg/mL
pka: 13.53±0.70(Predicted)
form: powder
color: white to off-white
InChIKey: PPUDLEUZKVJXSZ-VPCXQMTMSA-N

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M4949
Product name: 2’-C-Methylcytidine
Purity: ≥95% (HPLC), powder
Packaging: 5mg
Price: $97.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: M4949
Product name: 2’-C-Methylcytidine
Purity: ≥95% (HPLC), powder
Packaging: 25mg
Price: $388
Updated: 2024/03/01

Cayman Chemical

Product number: 22887
Product name: 2'-C-Methylcytidine
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 22887
Product name: 2'-C-Methylcytidine
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 22887
Product name: 2'-C-Methylcytidine
Purity: ≥98%
Packaging: 25mg
Price: $336
Updated: 2024/03/01

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2'-C-Methylcytidine Chemical Properties,Usage,Production

Description

2''-C-Methylcytidine (2CMC) is a ribonucleoside with broad-spectrum antiviral activity. It reduces the number of viral plaques in BHK-21 cells infected with dengue type 2, reovirus type 1, West Nile, and yellow fever RNA viruses with EC₅₀ values of 95, 26, 80, and 75 μM, respectively. 2CMC inhibits hepatitis C virus (HCV) replication (EC₅₀ = 2.2 μM in a replicon assay) and protects MDBK cells from infection with bovine virus diarrhea virus (BVDV; EC₅₀ = 2.2 μM) and human coronavirus (HCoV; EC₅₀ = 90 μM). It also reduces infectious virus yield in BHK-21 cells infected with foot-and-mouth disease virus (FMDV; EC₅₀ = 6.4 μM) and swine vesicular disease virus (SVDV; EC₅₀ = 45.2 μM). In vivo, 2CMC reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection.

Chemical Properties

White to Off-White Powder

Uses

2’-C-Methyl Cytidine (cas# 20724-73-6) is a compound useful in organic synthesis.

Biochem/physiol Actions

2′-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2′-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy. 2′-C-Methylcytidine was found to be effective against the 17D vaccine strain of yellow fever virus YFV in cell culture.

2'-C-Methylcytidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-C-Methylcytidine Suppliers

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View Lastest Price from 2'-C-Methylcytidine manufacturers

NewCan Biotech Limited

Product: 2'-C-methylCytidine 20724-73-6
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100g
Release date: 2024-06-03

Career Henan Chemical Co

Product: 2'-C-Methylcytidine 20724-73-6
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-08-05

20724-73-6, 2'-C-MethylcytidineRelated Search:

Cytidine 5’-monophosphate 5-METHYLCYTOSINE Cytidine Cytosine 5-Fluorocytidine Fluorocytosine Cytidine-5'-triphosphate disodium salt dihydrate 5-Azacytidine Cytarabine 2'-C-Methylguanosine 2'-C-Methyladenosine 2'-METHYLCYTIDINE-5'-TRIPHOSPHATE, DIAMMONIUM SALT Valopicitabine 2'-METHYLCYTIDINE-5'-MONOPHOSPHATE, DIAMMONIUM SALT 2',3',5'-Tri-O-benzoyl-2'-C-methyl-D-cytidine 2'-C-Methylcytidine

2'-C-METHYLCYTIDINE

2'-CMethyl-D-cytidine

2''-METHYLCYTIDINE

1-(2-C-Methyl-β-D-ribofuranosyl)cytosine

NM-107

2'-C-Methyl-1-β-D-ribofuranosylcytosine

-C-Methylcytidine

2'-C-METHYLCYTIDINE;NM-107;VALOPICITABINE

CS-2055

4-AMINO-1-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)-3-METHYLOXOLAN-2-YL]PYRIMIDIN-2-ONE

Cytidine, 2'-C-methyl-

2’-C-Methyl cytidine, 2’-C-Methyl-1-β-D-ribofuranosyl cytosine

2’-β-C-Methylcytidine

2'-C-Methylcytidine USP/EP/BP

4-Amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one

2’-b-C-Methyl cytidine NM107, HCV drug

2’-b-C-Methyl cytidine

4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one

NM 107,inhibit,Inhibitor,HCV,Hepatitis C virus,NM107

2’-C-Methyl cytidine

2’-b-C-Methyl cytidine

20724-73-6

C10H15N3O5

Bases & Related Reagents

Nucleotides