5'-DEOXYADENOSINE

ChemicalBook > CAS DataBase List > 5'-DEOXYADENOSINE

Description

Product Name: 5'-DEOXYADENOSINE
CAS No.: 4754-39-6
Chemical Name: 5'-DEOXYADENOSINE
Synonyms: 5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;Adenosine, 5'-deoxy-;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
CBNumber: CB5163003
Molecular Formula: C10H13N5O3
Formula Weight: 251.24
MOL File: 4754-39-6.mol

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5'-DEOXYADENOSINE Property

Melting point:: 210-212 °C
Boiling point:: 595.0±60.0 °C(Predicted)
Density: 1.93±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml
form: A crystalline solid
pka: 13.29±0.70(Predicted)
InChIKey: XGYIMTFOTBMPFP-KQYNXXCUSA-N

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Safety

WGK Germany: 3
RTECS: AU7358650

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D1771
Product name: 5′-Deoxyadenosine
Purity: methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
Packaging: 25mg
Price: $264
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 10mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 250mg
Price: $541
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 50mg
Price: $158
Updated: 2024/03/01

Cayman Chemical

Product number: 29619
Product name: 5''-Deoxyadenosine
Packaging: 100mg
Price: $296
Updated: 2024/03/01

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5'-DEOXYADENOSINE Chemical Properties,Usage,Production

Description

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis.

Uses

5′-Deoxyadenosine has been used:

as a standard in mass spectroscopy
as an inhibitor for screening thymidine phosphorylase activity
as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

Definition

ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.

Biochem/physiol Actions

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.

5'-DEOXYADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4754-39-6, 5'-DEOXYADENOSINERelated Search:

N6,N6-DIMETHYLADENOSINE ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE 2',3'-O-Isopropylideneadenosine 5'-Tosyladenosine 5'-(Methylthio)-5'-deoxyadenosine N6-BENZYLADENOSINE 2-Chloroadenosine Cyclic AMP Vidarabine Adenosine 5'-monophosphate monohydrate Bucladesine sodium 3'-ADENYLIC ACID 8-BROMOADENOSINE ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 5'-IODO-5'-DEOXYADENOSINE N6-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE DMT-dA(bz) Phosphoramidite N6-BZ-2'-DEOXYADENOSINE

5’-deoxy-adenosin

(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol

6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine

9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine

5'-DEOXYADENOSINE

Adenosine, 5'-deoxy-

5′-dAdo

2'-Deoxycytidine Monohydrate(2'-dC ? H?O)

5'-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate

(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol

inhibit,5'DEOXYADENOSINE,5'-Deoxyadenosine,Endogenous Metabolite,Inhibitor,Orthopoxvirus,5' DEOXYADENOSINE

5'-DEOXYADENOSINE

4754-39-6

BioChemical

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides

Biochemicals and Reagents

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides