ChemicalBook > CAS DataBase List > 5-CHLORO-1H-INDOLE-2-CARBALDEHYDE

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE

Product Name: 5-CHLORO-1H-INDOLE-2-CARBALDEHYDE
CAS No.: 53590-49-1
Chemical Name: 5-CHLORO-1H-INDOLE-2-CARBALDEHYDE
Synonyms: 5-chloro-indole-2-carbaldehyde;5-Chloroindole-2-carboxaldehyde;5-CHLORO-1H-INDOLE-2-CARBALDEHYDE;1H-Indole-2-carboxaldehyde, 5-chloro-;5-Chloro-1H-indole-2-carbaldehyde ,97%
CBNumber: CB5166145
Molecular Formula: C9H6ClNO
Formula Weight: 179.6
MOL File: 53590-49-1.mol

Less

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE Property

Melting point:: 204-206 °C
Boiling point:: 373.4±22.0 °C(Predicted)
Density: 1.431±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 14.14±0.30(Predicted)
Appearance: Off-white to brown Solid

Less

Safety

Hazard Codes: Xi
Risk Statements: 36-20/21/22
Safety Statements: 26-36/37
HazardClass: IRRITANT
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: C588215
Product name: 5-Chloro-1H-indole-2-carbaldehyde
Packaging: 100mg
Price: $130
Updated: 2021/12/16

TRC

Product number: C588215
Product name: 5-Chloro-1H-indole-2-carbaldehyde
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR930619
Product name: 5-Chloro-1H-indole-2-carbaldehyde
Purity: 95%
Packaging: 250mg
Price: $215
Updated: 2021/12/16

AK Scientific

Product number: Z2968
Product name: 5-Chloroindole-2-carboxaldehyde
Packaging: 250mg
Price: $172
Updated: 2021/12/16

Matrix Scientific

Product number: 016207
Product name: 5-Chloro-1H-indole-2-carbaldehyde
Packaging: 500mg
Price: $184
Updated: 2021/12/16

Less

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Synthesis

53590-47-9

53590-49-1

General procedure for the synthesis of 5-chloro-1H-indole-2-carboxaldehyde from (5-chloro-1H-indol-2-yl)methanol: (5-chloro-1H-indol-2-yl)methanol (1 eq.) was dissolved in tetrahydrofuran (THF, 0.5 M), manganese dioxide (3 eq.) was added, the reaction was stirred for 1.5 hr. at room temperature, and the progress of the reaction was monitored by thin layer chromatography (TLC) until the complete conversion of the feedstock. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad, the filtrate was dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent to give the crude 5-chloro-1H-indole-2-carbaldehyde in 82% yield.

References

[1] Synlett, 2007, # 11, p. 1707 - 1710
[2] Chemical Communications, 2013, vol. 49, # 28, p. 2894 - 2896
[3] Patent: US2008/9485, 2008, A1. Location in patent: Page/Page column 41
[4] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 561 - 577
[5] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 6, p. 1889 - 1900

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

4-Chlorophenylhydrazine hydrochloride Ethanol Ethyl pyruvate Manganese dioxide Polyphosphoric acid Tetrahydrofuran Lithium Aluminum Hydride

Preparation Products

Less

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE Suppliers

China 49 India 2 United States 8 Global 59

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4894
Advantage: 55

Nanjing Huang Tai Pharmaceutical Technology Co. Ltd.

Tel: 025-58803135 18551845925
Fax: 025-58803650
Email: 3569572487@qq.com
Country: China
ProdList: 337
Advantage: 58

Shanghai Kahn Pharmaceutical Co., Ltd.

Tel: 021-34979681; 17701870669
Fax: 021-34979681
Email: 41513101@qq.com
Country: China
ProdList: 1785
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12475
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9853
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Medicil Biomedical Co., Ltd.

Tel: 021-50822001
Email: marketing@medicilon.com.cn
Country: China
ProdList: 1152
Advantage: 58

Shanghai Union Medical Technology Co. Ltd.

Tel: 13120563767
Fax: 15669989863
Email: chemchen925@outlook.com
Country: China
ProdList: 987
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9947
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shanghai Chino Pharmaceutical Technology Co., Ltd

Tel: 021-021-51557188 15901710861
Fax: QQ: 569058060
Email: sales@channelpharm.com
Country: China
ProdList: 1228
Advantage: 58

Hebei Weite Medical Technology Co., Ltd

Tel: 13180081292 13180081292
Email: contact@wetogethermed.com
Country: China
ProdList: 7943
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8886
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Hangzhou Hongxi Biomedical Technology Co., LTD

Tel: 18989489206
Email: hoxipharm@163.com
Country: China
ProdList: 4921
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 029-029-81148929 17791530722
Email: 1049@dideu.com
Country: China
ProdList: 10011
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

Shanghai Shengxiu Biotechnology Co., Ltd.

Tel: 13761144602
Email: 3896578657@qq.com
Country: China
ProdList: 4483
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Chongqing Xuhan Technology Co., Ltd

Tel: 13668063927
Email: 489466966@qq.com
Country: China
ProdList: 946
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49934
Advantage: 58

PT CHEM GROUP LIMITED

Tel: +86-85511178;
Email: peter68@ptchemgroup.com
Country: China
ProdList: 35425
Advantage: 58

Gihi Chemicals Co., Limited

Tel: +86-0571-86217390 +8618058761490
Email: info@gihichem.com
Country: China
ProdList: 998
Advantage: 58

Changzhou Ansciep Chemical Co., Ltd.

Tel: +86 519 86305871
Fax: +86 519 86305879
Email: sales@ansciepchem.com
Country: CHINA
ProdList: 4241
Advantage: 58

Guangzhou Tangsui Technology Co., Ltd.

Tel: 13725272260
Country: CHINA
ProdList: 0
Advantage: 58

Guangzhou Zhenhao Biotechnology Co., Ltd.

Tel: 13430395027
Country: CHINA
ProdList: 115
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

53590-49-1, 5-CHLORO-1H-INDOLE-2-CARBALDEHYDERelated Search:

5-Chloroindole-2-carboxylic acid Ethyl 5-chloro-2-indolecarboxylate 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE 5-CHLORO-N-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-1H-INDOLE-2-CARBOXAMIDE Ethyl 3-amino-5-chloro-1H-indole-2-carboxylate 5-CHLORO-3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER ETHYL 5-CHLORO-3-METHYL-1H-INDOLE-2-CARBOXYLATE 6-CHLORO-(PHENYLSULFONYL)-1H-INDOLE-3-CARBOXAMIDE 5-CHLORO-3-PHENYL-1H-INDOLE-2-CARBOXYLIC ACID 5,7-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID 6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one ETHYL 5-CHLORO-3-PHENYL-1H-INDOLE-2-CARBOXYLATE AKOS JY2083294 3-(2-AMINOETHYL)-5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID 5-chloro-3-phenylthioindole-2-carboxamide 3-ACETYLAMINO-5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID 5-CHLORO-1-(4-NITROBENZYL)-3-PHENYL-1H-INDOLE-2-CARBOXAMIDE 5-CHLORO-3-PHENYL-1H-INDOLE-2-CARBOXAMIDE

5-CHLORO-1H-INDOLE-2-CARBALDEHYDE

5-chloro-indole-2-carbaldehyde

1H-Indole-2-carboxaldehyde, 5-chloro-

5-Chloro-1H-indole-2-carbaldehyde ,97%

5-Chloroindole-2-carboxaldehyde

53590-49-1