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3-N-Butylphthalide

Product Name
3-N-Butylphthalide
CAS No.
6066-49-5
Chemical Name
3-N-Butylphthalide
Synonyms
butylphthalide;3-Butylphthalide;3-n-Butylphathlide;3-Butylisobenzofuran-1(3H)-one;Butylphathlide;3-butyl-1(3H)-Isobenzofuranone;FEMA 3334;BUTYLPHTHALIDE, 3-n-(P);CL234;Butylphthalein
CBNumber
CB5174179
Molecular Formula
C12H14O2
Formula Weight
190.24
MOL File
6066-49-5.mol
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3-N-Butylphthalide Property

Boiling point:
265.75°C (rough estimate)
Density 
1.0527 (rough estimate)
refractive index 
1.5197 (estimate)
FEMA 
3334 | 3-N-BUTYLPHTHALIDE
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly); Almost insoluble in water, soluble in alcohol and oils.
form 
Oil
color 
Colourless to Yellow
Odor
at 10.00 % in dipropylene glycol. herbal phenolic celery
Odor Type
herbal
JECFA Number
1169
Stability:
Hygroscopic
LogP
2.80
NIST Chemistry Reference
3-Butylphthalide(6066-49-5)
EPA Substance Registry System
1(3H)-Isobenzofuranone, 3-butyl- (6066-49-5)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00312
Product name
3-N-Butylphthalide
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$263
Updated
2025/07/31
TCI Chemical
Product number
B6520
Product name
Butylphthalide
Purity
min. 98.0 %
Packaging
1G
Price
$112
Updated
2025/07/31
TCI Chemical
Product number
B6520
Product name
Butylphthalide
Purity
min. 98.0 %
Packaging
5G
Price
$336
Updated
2025/07/31
Cayman Chemical
Product number
30284
Product name
(±)-Butylphthalide
Packaging
500mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
30284
Product name
(±)-Butylphthalide
Packaging
1g
Price
$121
Updated
2024/03/01
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3-N-Butylphthalide Chemical Properties,Usage,Production

Chemical Properties

3-N-Butylphthalide has a warm, spicy herbaceous odor.

Occurrence

Reported found in Levisticum officinale (lovage) and L. acutilobum; also in celery oil.

Uses

3-Butylphthalide is a cardiovascular drug used for the treatment of cerebral ischemic stroke. This interesting Lactone finds use in the composing of meat flavors, spice blends, etc. 

Preparation

From celery oil; from phthalide via bromination and subsequent reaction of the resulting phthalidic acid with n-butyl magnesium bromide.

Definition

ChEBI: Butylphthalide is a member of benzofurans.

Aroma threshold values

Detection: 5 ppb

3-N-Butylphthalide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-N-Butylphthalide Suppliers

Shijiazhuang Coshine Chemical Co.,Ltd
Tel
18633820607 18633820607
Email
377964081@qq.com
Country
China
ProdList
93
Advantage
58
Shijiazhuang Qiyue Chemical Co. LTD
Tel
15369111890
Fax
15369111890
Email
sjzqiyuekeji@163.com
Country
China
ProdList
305
Advantage
58
Allikang Pharmaceutical Co., LTD
Tel
0573-87390950 13806705416
Email
wzj@alicornpharma.com
Country
China
ProdList
57
Advantage
58
Nanjing Yikangda Pharmaceutical Technology Co.LTD
Tel
18118984557; 18118984557
Email
753016615@qq.com
Country
China
ProdList
498
Advantage
58
Shijiazhuang C-element Biotech Co.,Ltd
Tel
18033710157
Email
Lisa@C-elementBiotech.com
Country
China
ProdList
118
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
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View Lastest Price from 3-N-Butylphthalide manufacturers

Zhengzhou Anbu Chem Co.,Ltd
Product
3-N-Butylphthalide 6066-49-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000KGS
Release date
2025-07-30
Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-N-BUTYLPHTHALIDE 6066-49-5
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-13
Henan Aochuang Chemical Co.,Ltd.
Product
3-N-BUTYLPHTHALIDE 6066-49-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-09

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