CYTOCHALASIN E
- Product Name
- CYTOCHALASIN E
- CAS No.
- 36011-19-5
- Chemical Name
- CYTOCHALASIN E
- Synonyms
- CYTOCHALACINE;CYTOCHALICINE;CYTOCHALASIN E;CYTOCHALASIN 3;CYTOCHALASIN E(RG);CYTOCHALASIN E USP/EP/BP;LAJXCUNOQSHRJO-DXUWGLIISA-N;CYTOCHALASIN E(RG) Please Call;CYTOCHALASIN E, ASPERGILLUS CLAVATUS;CYTOCHALASIN E FROM ASPERGILLUSCLAVATUS
- CBNumber
- CB5192252
- Molecular Formula
- C28H33NO7
- Formula Weight
- 495.56
- MOL File
- 36011-19-5.mol
CYTOCHALASIN E Property
- Melting point:
- 206 °C
- Boiling point:
- 587.59°C (rough estimate)
- Density
- 1.2415 (rough estimate)
- refractive index
- 1.6290 (estimate)
- storage temp.
- -20°C
- solubility
- DMF: 11 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml
- form
- White solid.
- pka
- 11.22±0.70(Predicted)
- color
- White to off-white
- BRN
- 1096975
- LogP
- 1.920 (est)
Safety
- Hazard Codes
- T+,T
- Risk Statements
- 26/27/28-63
- Safety Statements
- 28-36/37-45
- RIDADR
- UN 1544 6.1/PG 2
- WGK Germany
- 3
- RTECS
- HA5360000
- F
- 10
- HazardClass
- 6.1(a)
- PackingGroup
- I
- HS Code
- 29349990
- Hazardous Substances Data
- 36011-19-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H330Fatal if inhaled
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- C2149
- Product name
- Cytochalasin E from Aspergillus clavatus
- Packaging
- 1mg
- Price
- $275
- Updated
- 2022/05/15
- Product number
- C2149
- Product name
- Cytochalasin E from Aspergillus clavatus
- Packaging
- 5mg
- Price
- $1080
- Updated
- 2022/05/15
- Product number
- 11331
- Product name
- Cytochalasin E
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $67
- Updated
- 2024/03/01
- Product number
- 11331
- Product name
- Cytochalasin E
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $266
- Updated
- 2024/03/01
- Product number
- 11331
- Product name
- Cytochalasin E
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $498
- Updated
- 2024/03/01
CYTOCHALASIN E Chemical Properties,Usage,Production
Description
The cytochalasins are cell-
Chemical Properties
white powder
Uses
Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. Despite the common mode of action, there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, does not inhibit glucose transport.
Uses
Cytochalasin E is a fungal metabolite which has been shown to exhibit antimicrobial and antibacterial effects. Cytochalasin E is a microfilament inhibitor enhancing the low-affinity Fc epsilon receptor (CD23) expression.
Uses
Cytochalasin E has been used as:
- a toxin to study its effects on avocado plants
- a component of the incubating medium in feline junctional adhesion molecule 1 (fJAM-1) expression assay
- an inhibitor of actin polymerization to study its effects on mitochondria uptake by mice endothelial cells
Definition
ChEBI: A natural product found in Arthrinium sacchari.
Biochem/physiol Actions
Cytochalasin E is an epoxide that exhibits anti-proliferative activity in endothelial cells in vitro. It also participates in inhibiting tumor growth and angiogenesis in vivo. Cytochalasin E also possesses antimicrobial and antiviral properties.
CYTOCHALASIN E Preparation Products And Raw materials
Raw materials
Preparation Products
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