CYTOCHALASIN A

Product Name: CYTOCHALASIN A
CAS No.: 14110-64-6
Chemical Name: CYTOCHALASIN A
Synonyms: Dehydrophomin;CYTOCHALASIN A;CYTOCHALASIN A(RG);5,5-Didehydrophomin;Cytochalasin dreschslera dematioidea;CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA;CytochalasinA from Drechslera dematioidea;cytochalasin a from helminthosporium dematioideum;Cytochalasin A 5-Dehydrophomin Dehydrophomin;CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA, BIOCHEMIKA, >= 99.0% (TLC)
CBNumber: CB6735221
Molecular Formula: C29H35NO5
Formula Weight: 477.59
MOL File: 14110-64-6.mol

More

Less

CYTOCHALASIN A Property

Melting point:: 190-191 °C
Boiling point:: 725.1±60.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: ethanol: 20 mg/mL, clear, colorless
form: Powder
pka: 13.54±0.70(Predicted)
color: White
Water Solubility: Soluble in DMF, DMSO, ethanol and acetone. Insoluble in water.
Sensitive: Light Sensitive
BRN: 949521
LogP: 1.849 (est)
EPA Substance Registry System: Cytochalasin A (14110-64-6)

More

Less

Safety

Hazard Codes: T+,T
Risk Statements: 26/27/28-63
Safety Statements: 28-36/37-45
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3
F: 10
HazardClass: 6.1(a)
PackingGroup: I
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C6637
Product name: Cytochalasin A from Drechslera dematioidea
Packaging: 1mg
Price: $163
Updated: 2024/03/01

Alfa Aesar

Product number: J60280
Product name: Cytochalasin A
Packaging: 1mg
Price: $91.6
Updated: 2021/12/16

Alfa Aesar

Product number: J60280
Product name: Cytochalasin A
Packaging: 5mg
Price: $352
Updated: 2021/12/16

Cayman Chemical

Product number: 11327
Product name: Cytochalasin A
Purity: ≥98%
Packaging: 1mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 11327
Product name: Cytochalasin A
Purity: ≥98%
Packaging: 5mg
Price: $195
Updated: 2024/03/01

More

Less

CYTOCHALASIN A Chemical Properties,Usage,Production

Description

The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin A is an oxidized analog of cytochalasin B which uniquely inhibits HIV-1 protease (IC₅₀ = 3 μM). Cytochalasins A and B differ from other cytochalasins in being able to rapidly and reversibly inhibit glucose transport by competitively binding glucose transporters (K_i = 4.0 and 0.6 μM, respectively). Cytochalasin A also induces the phosphorylation of the tyrosine phosphatase PTP3 of Dictyostelium, activating STATc.

Chemical Properties

white powder

Uses

Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin A exhibits potent inhibition of actin filament function leading to cell death by apoptosis, and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of the class display diverse selectivity. Specifically, cytochalasin A is one of the few cytochalasins exhibiting activity against HIV-1 protease.

Uses

Cytochalasin A binds to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Preventing growth and sugar uptake in a Saccharomyces strain.

Definition

ChEBI: Cytochalasin A is a cytochalasin.

Biochem/physiol Actions

Cytochalasin A reacts with sulfhydryls, and inhibits growth and glucose transport in Saccharomyces. Cytochalasin A is an oxidizing analog of cytochalsin B.

CYTOCHALASIN A Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CYTOCHALASIN A Suppliers

Australia 1 Belgium 1 China 59 Germany 4 India 2 Japan 1 Switzerland 3 United Kingdom 9 United States 19 Global 99

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9353
Advantage: 58

14110-64-6, CYTOCHALASIN ARelated Search:

CYTOCHALASIN D CYTOCHALASIN C CYTOCHALASIN B, DIHYDRO CYTOCHALASIN B CYTOCHALASIN E 6-PHENYL-1-HEXANOL 4-Penten-1-ol 1-Amino-2-methylpropan-2-ol CYTOCHALASIN A TRANS-2-OCTENOIC ACID 1,3-Dimethylamylamine LACTAMIDE 2,2-DI-N-PROPYLACETAMIDE 1,7-Octadiene 2,5-DIMETHYLCYCLOHEXANOL 2-(N-PENTYLAMINO)ETHANOL 3-Methyl-1,3-butanediol 8-PHENYL-1-OCTANOL

(7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione

5,5-Didehydrophomin

Dehydrophomin

Cytochalasin dreschslera dematioidea

Cytochalasin A 5-Dehydrophomin Dehydrophomin

7(S)-hydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,20,23-trione

2H-Oxacyclotetradecino2,3-disoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-

CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA

CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA, BIOCHEMIKA, >= 99.0% (TLC)

CYTOCHALASIN A

cytochalasin a from helminthosporium dematioideum

CYTOCHALASIN A(RG)

CytochalasinA from Drechslera dematioidea

14110-64-6

C29H35NO5

Other

Cytoskeleton and Extracellular Matrix

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors

Enzyme Inhibitors by Type

Cell Biology

Cell Signaling and Neuroscience

Biochemicals and Reagents

BioChemical

Actin Inhibitors and Probes

Actin Inhibitors and ProbesCell Signaling and Neuroscience

Cell Signaling and Neuroscience

antibiotic

Cytoskeleton and Extracellular Matrix

Mold

Toxins and Venoms