1-(2-Chlorophenyl)piperazine hydrochloride

Product Name: 1-(2-Chlorophenyl)piperazine hydrochloride
CAS No.: 41202-32-8
Chemical Name: 1-(2-Chlorophenyl)piperazine hydrochloride
Synonyms: TIMTEC-BB SBB003263;LABOTEST-BB LT00454957;LABOTEST-BB LT00159499;Trazodone Impurity 9 HCl;Trazodone Impurity 7 HCl;Trazodone Impurity 33 HCl;2-CHLOROPHENYL PIPERAZINE HCL;1-(2-CHLOROPHENYL)PIPERAZINE HCL;2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE;1-(2-chlorophenyl)piperazinium chloride
CBNumber: CB5196290
Molecular Formula: C10H14Cl2N2
Formula Weight: 233.14
MOL File: 41202-32-8.mol

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1-(2-Chlorophenyl)piperazine hydrochloride Property

Melting point:: 160-163 °C (dec.)(lit.)
storage temp.: Store at room temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White
Sensitive: Hygroscopic
BRN: 5652889
CAS DataBase Reference: 41202-32-8(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C67605
Product name: 1-(2-Chlorophenyl)piperazine monohydrochloride
Purity: 95%
Packaging: 10g
Price: $112
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FC36602
Product name: 1-(2-Chlorophenyl)-piperazine hydrochloride
Packaging: 25g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC36602
Product name: 1-(2-Chlorophenyl)-piperazine hydrochloride
Packaging: 50g
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC36602
Product name: 1-(2-Chlorophenyl)-piperazine hydrochloride
Packaging: 100g
Price: $300
Updated: 2021/12/16

Matrix Scientific

Product number: 074236
Product name: 1-(2-Chlorophenyl)piperazine hydrochloride
Purity: 95+%
Packaging: 5g
Price: $10
Updated: 2021/12/16

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1-(2-Chlorophenyl)piperazine hydrochloride Chemical Properties,Usage,Production

Uses

1-(2-Chlorophenyl)piperazine Hydrochloride is a reactant used in the preparation of piperazinyl, phenylpiperidinyl, tetrahydropyridinyl, and tetrahydropyridoindolylbutylbenzindoles with 5-hydroxytryptamine receptor antagonist activity.

Synthesis

1104513-49-6

41202-32-8

To a stirred solution of tert-butyl 4-(2-chlorophenyl)piperazine-1-carboxylate (250 mg, 0.844 mmol) in 1,4-dioxane (2 mL) was added slowly and dropwise a 1,4-dioxane solution (0.9 mL, 3.60 mmol) in 4 N HCl at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h (complete consumption of feedstock was confirmed by TLC monitoring). Upon completion of the reaction, the volatile solvent was removed under reduced pressure to give the crude product. The crude product was washed with ether (2 x 20 mL) and dried under high vacuum to yield 1-(2-chlorophenyl)piperazine hydrochloride (165 mg, 84% yield) as a white solid.

References

[1] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 45; 46

1-(2-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-Chlorophenyl)piperazine hydrochloride Suppliers

China 116 Europe 1 Germany 4 India 6 Italy 1 Japan 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 7 United States 22 Global 161

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
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Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
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Advantage: 64

Pure Chemistry Scientific Inc.

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Fax: 001-617-206-9595
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Country: United States
ProdList: 10186
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Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
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Country: China
ProdList: 42934
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China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

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View Lastest Price from 1-(2-Chlorophenyl)piperazine hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 1-(2-Chlorophenyl)piperazine hydrochloride 41202-32-8
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-24

Shaanxi Dideu Medichem Co. Ltd

Product: 1-(2-Chlorophenyl) piperazine 41202-32-8
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2020-01-14

Shaanxi Dideu Medichem Co. Ltd

Product: 1-(2-Chlorophenyl) piperazine 41202-32-8
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2020-01-14

41202-32-8, 1-(2-Chlorophenyl)piperazine hydrochlorideRelated Search:

Piperazine Triphenylmethyl Chloride Chlorodimethylphenylsilane Topotecan hydrochloride tert-Butylchlorodiphenylsilane CHLOROPHENYLSILANE Aripiprazole 1-(2,3-Dichlorophenyl)piperazine hydrochloride 1-(2,4-DICHLOROPHENYL)-PIPERAZINE DIHYDROCHLORIDE Acaprazine Propiophenone 1-(3-Chlorophenyl)piperazine hydrochloride N-(3,4-DICHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 1-(4-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 1-(4-Chlorophenyl)piperazine dihydrochloride 1-(2,3-Dichlorophenyl)-piperazine 1-(3-Chlorophenyl)piperazine hydrochloride,1-(3-Chlorophenyl)piperazine hydrochloride DEHYDRO ARIPIPRAZOLE

TIMTEC-BB SBB003263

LABOTEST-BB LT00159499

LABOTEST-BB LT00454957

1-(O-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE

N-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE

1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE

1-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE

1-(2-chlorophenyl)piperazinium chloride

1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 99%

1-(2-CHLOROPHENYL)PIPERAZINE HCL

2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE

2-CHLOROPHENYL PIPERAZINE HCL

1-(2-Chlorophenyl)piperazine monohydrochloride monohydrate, 98%

1-(2-Chlorophenyl)piperazine monohydrochloride 95%

ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl)

Trazodone Impurity 33 HCl

Trazodone Impurity 9 HCl

Trazodone Impurity 7 HCl

ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl) 1.0 mg/ml in Methanol (as free base)

41202-32-8

C10H15Cl3N2

C10H14C12N2

AMINE

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Heterocyclic Building Blocks

Halogenated Heterocycles

Piperazines

Piperidines, Piperidones, Piperazines

PiperazineDerivative

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Halogenated Heterocycles

Heterocyclic Building Blocks

Piperazines

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