ChemicalBook > CAS DataBase List > 1-(2-Chlorophenyl)piperazine hydrochloride

1-(2-Chlorophenyl)piperazine hydrochloride

Product Name
1-(2-Chlorophenyl)piperazine hydrochloride
CAS No.
41202-32-8
Chemical Name
1-(2-Chlorophenyl)piperazine hydrochloride
Synonyms
TIMTEC-BB SBB003263;LABOTEST-BB LT00454957;LABOTEST-BB LT00159499;Trazodone Impurity 9 HCl;Trazodone Impurity 7 HCl;Trazodone Impurity 33 HCl;2-CHLOROPHENYL PIPERAZINE HCL;1-(2-CHLOROPHENYL)PIPERAZINE HCL;2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE;1-(2-chlorophenyl)piperazinium chloride
CBNumber
CB5196290
Molecular Formula
C10H14Cl2N2
Formula Weight
233.14
MOL File
41202-32-8.mol
More
Less

1-(2-Chlorophenyl)piperazine hydrochloride Property

Melting point:
160-163 °C (dec.)(lit.)
storage temp. 
Store at room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White
Sensitive 
Hygroscopic
BRN 
5652889
CAS DataBase Reference
41202-32-8(CAS DataBase Reference)
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C67605
Product name
1-(2-Chlorophenyl)piperazine monohydrochloride
Purity
95%
Packaging
10g
Price
$112
Updated
2025/07/31
Matrix Scientific
Product number
074236
Product name
1-(2-Chlorophenyl)piperazine hydrochloride
Purity
95+%
Packaging
5g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
074236
Product name
1-(2-Chlorophenyl)piperazine hydrochloride
Purity
95+%
Packaging
25g
Price
$28
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC36602
Product name
1-(2-Chlorophenyl)-piperazine hydrochloride
Packaging
10g
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
074236
Product name
1-(2-Chlorophenyl)piperazine hydrochloride
Purity
95+%
Packaging
100g
Price
$105
Updated
2021/12/16
More
Less

1-(2-Chlorophenyl)piperazine hydrochloride Chemical Properties,Usage,Production

Uses

1-(2-Chlorophenyl)piperazine Hydrochloride is a reactant used in the preparation of piperazinyl, phenylpiperidinyl, tetrahydropyridinyl, and tetrahydropyridoindolylbutylbenzindoles with 5-hydroxytryptamine receptor antagonist activity.

Synthesis

1104513-49-6

41202-32-8

To a stirred solution of tert-butyl 4-(2-chlorophenyl)piperazine-1-carboxylate (250 mg, 0.844 mmol) in 1,4-dioxane (2 mL) was added slowly and dropwise a 1,4-dioxane solution (0.9 mL, 3.60 mmol) in 4 N HCl at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h (complete consumption of feedstock was confirmed by TLC monitoring). Upon completion of the reaction, the volatile solvent was removed under reduced pressure to give the crude product. The crude product was washed with ether (2 x 20 mL) and dried under high vacuum to yield 1-(2-chlorophenyl)piperazine hydrochloride (165 mg, 84% yield) as a white solid.

References

[1] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 45; 46

1-(2-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-(2-Chlorophenyl)piperazine hydrochloride Suppliers

China 116 Europe 1 Germany 4 India 6 Italy 1 Japan 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 7 United States 22 Global 161
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
More
Less

View Lastest Price from 1-(2-Chlorophenyl)piperazine hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-(2-Chlorophenyl)piperazine hydrochloride 41202-32-8
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Shaanxi Dideu Medichem Co. Ltd
Product
1-(2-Chlorophenyl) piperazine 41202-32-8
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-14
Shaanxi Dideu Medichem Co. Ltd
Product
1-(2-Chlorophenyl) piperazine 41202-32-8
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-14

41202-32-8, 1-(2-Chlorophenyl)piperazine hydrochlorideRelated Search:

Piperazine Triphenylmethyl Chloride Chlorodimethylphenylsilane Topotecan hydrochloride tert-Butylchlorodiphenylsilane CHLOROPHENYLSILANE Aripiprazole 1-(2,3-Dichlorophenyl)piperazine hydrochloride 1-(2,4-DICHLOROPHENYL)-PIPERAZINE DIHYDROCHLORIDE Acaprazine Propiophenone 1-(3-Chlorophenyl)piperazine hydrochloride N-(3,4-DICHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 1-(4-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 1-(4-Chlorophenyl)piperazine dihydrochloride 1-(2,3-Dichlorophenyl)-piperazine 1-(3-Chlorophenyl)piperazine hydrochloride,1-(3-Chlorophenyl)piperazine hydrochloride DEHYDRO ARIPIPRAZOLE

  • TIMTEC-BB SBB003263
  • LABOTEST-BB LT00159499
  • LABOTEST-BB LT00454957
  • 1-(O-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE
  • N-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE
  • 1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE
  • 1-(2-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE
  • 1-(2-chlorophenyl)piperazinium chloride
  • 1-(2-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE 99%
  • 1-(2-CHLOROPHENYL)PIPERAZINE HCL
  • 2-CHLOROPHENYLPIPERAZINE HYDROCHLORIDE
  • 2-CHLOROPHENYL PIPERAZINE HCL
  • 1-(2-Chlorophenyl)piperazine monohydrochloride monohydrate, 98%
  • 1-(2-Chlorophenyl)piperazine monohydrochloride 95%
  • ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl)
  • Trazodone Impurity 33 HCl
  • Trazodone Impurity 9 HCl
  • Trazodone Impurity 7 HCl
  • ortho-Chlorophenylpiperazine Hydrochloride (oCPP HCl) 1.0 mg/ml in Methanol (as free base)
  • 41202-32-8
  • C10H15Cl3N2
  • C10H14C12N2
  • AMINE
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Piperazines
  • Piperidines, Piperidones, Piperazines
  • PiperazineDerivative
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Piperazines
  • PiperazinesHeterocyclic Building Blocks